ENSMUSG00000024510


Mus musculus

Features
Gene ID: ENSMUSG00000024510
  
Biological name :Ftmt
  
Synonyms : Ferritin, mitochondrial / Ftmt / Q9D5H4
  
Possible biological names infered from orthology : Q8N4E7
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: D1
Gene start: 52331536
Gene end: 52332986
  
Corresponding Affymetrix probe sets: 10455691 (MoGene1.0st)   1421347_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025388
NCBI entrez gene - 67634     See in Manteia.
MGI - MGI:1914884
RefSeq - NM_026286
RefSeq Peptide - NP_080562
swissprot - Q9D5H4
Ensembl - ENSMUSG00000024510
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fth1aENSDARG00000015551Danio rerio
 fth1bENSDARG00000007975Danio rerio
 FTMTENSG00000181867Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fth1 / P09528 / Ferritin heavy chain Ferritin heavy chain, N-terminally processed / P02794* / ferritin heavy chain 1*ENSMUSG0000002466160
Fthl17b / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007820841
Fthl17c / Mus musculus ferritin, heavy polypeptide-like 17, pseudo 1 (Fthl17-ps1), mRNA. / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000006068541
Ftl1 / FTL* / P02792* / ferritin light chain*ENSMUSG0000005070838
Fthl17f / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007224938
Fthl17 / Q99MX2 / Ferritin heavy polypeptide-like 17 / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007181538
Fthl17d / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007820638
Ftl1-ps1 / FTL* / P02792* / ferritin light chain*ENSMUSG0000006238238
Fthl17a / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000003549135


Protein motifs (from Interpro)
Interpro ID Name
 IPR001519  Ferritin
 IPR008331  Ferritin/DPS protein domain
 IPR009040  Ferritin-like diiron domain
 IPR009078  Ferritin-like superfamily
 IPR012347  Ferritin-like
 IPR014034  Ferritin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006826 iron ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis TAS
 biological_processGO:0006880 intracellular sequestering of iron ion IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0051349 positive regulation of lyase activity IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1904231 positive regulation of succinate dehydrogenase activity IEA
 biological_processGO:1904234 positive regulation of aconitate hydratase activity IEA
 cellular_componentGO:0005739 mitochondrion TAS
 molecular_functionGO:0004322 ferroxidase activity TAS
 molecular_functionGO:0005506 iron ion binding TAS
 molecular_functionGO:0008199 ferric iron binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024510 Ftmt / Q9D5H4 / Ferritin, mitochondrial / Q8N4E7*  / complex






 

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