ENSMUSG00000050708


Mus musculus

Features
Gene ID: ENSMUSG00000050708
  
Biological name :Ftl1
  
Synonyms : Ftl1
  
Possible biological names infered from orthology : ferritin light chain / FTL / P02792
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 45457944
Gene end: 45459884
  
Corresponding Affymetrix probe sets: 10406198 (MoGene1.0st)   10447591 (MoGene1.0st)   10508069 (MoGene1.0st)   10563295 (MoGene1.0st)   1418364_a_at (Mouse Genome 430 2.0 Array)   1422301_at (Mouse Genome 430 2.0 Array)   1422302_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092002
Ensembl peptide - ENSMUSP00000147526
Ensembl peptide - ENSMUSP00000147389
NCBI entrez gene - 14325     See in Manteia.
MGI - MGI:95589
RefSeq - NM_010240
RefSeq Peptide - NP_034370
swissprot - A0A1B0GRH4
swissprot - A0A1B0GR60
swissprot - Q9CPX4
Ensembl - ENSMUSG00000050708
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FTLENSG00000087086Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ftl1-ps1 / FTL* / P02792* / ferritin light chain*ENSMUSG00000062382100
Fth1 / P09528 / Ferritin heavy chain Ferritin heavy chain, N-terminally processed / P02794* / ferritin heavy chain 1*ENSMUSG0000002466150
Ftmt / Q9D5H4 / Ferritin, mitochondrial / Q8N4E7*ENSMUSG0000002451050
Fthl17c / Mus musculus ferritin, heavy polypeptide-like 17, pseudo 1 (Fthl17-ps1), mRNA. / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000006068542
Fthl17b / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007820842
Fthl17f / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007224942
Fthl17 / Q99MX2 / Ferritin heavy polypeptide-like 17 / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007181540
Fthl17d / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000007820640
Fthl17a / FTHL17* / Q9BXU8* / ferritin heavy chain like 17*ENSMUSG0000003549135


Protein motifs (from Interpro)
Interpro ID Name
 IPR001519  Ferritin
 IPR008331  Ferritin/DPS protein domain
 IPR009040  Ferritin-like diiron domain
 IPR009078  Ferritin-like superfamily
 IPR012347  Ferritin-like
 IPR014034  Ferritin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006826 iron ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0008199 ferric iron binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis
Neutrophil degranulation
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001396 unidirectional circling "circling behavior in one direction only, either clockwise or counterclockwise" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fth1tm1.1Ruvi/Fth1tm1.1Ruvi,Ftl1tm1.1Ruvi/Ftl1tm1.1Ruvi
Genetic Background: involves: 129 * C57BL/6

 MP:0005191 head tilt "condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fth1tm1.1Ruvi/Fth1tm1.1Ruvi,Ftl1tm1.1Ruvi/Ftl1tm1.1Ruvi
Genetic Background: involves: 129 * C57BL/6

 MP:0008248 abnormal mononuclear phagocyte morphology "any structural anomaly of a vertebrate phagocyte with a single nucleus" [CL:0000113]
Show

Allelic Composition: Fth1tm1.1Ruvi/Fth1tm1.1Ruvi,Ftl1tm1.1Ruvi/Ftl1tm1.1Ruvi
Genetic Background: involves: 129 * C57BL/6

 MP:0008743 decreased liver iron level "reduction in the amount of iron present in the liver tissue" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fth1tm1.1Ruvi/Fth1tm1.1Ruvi,Ftl1tm1.1Ruvi/Ftl1tm1.1Ruvi
Genetic Background: involves: 129 * C57BL/6

 MP:0008810 increased circulating iron level "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fth1tm1.1Ruvi/Fth1tm1.1Ruvi,Ftl1tm1.1Ruvi/Ftl1tm1.1Ruvi
Genetic Background: involves: 129 * C57BL/6

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Fth1tm1.1Ruvi/Fth1tm1.1Ruvi
Genetic Background: involves: 129 * C57BL/6

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Fth1tm1.1Ruvi/Fth1tm1.1Ruvi,Ftl1tm1.1Ruvi/Ftl1tm1.1Ruvi
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028580 Pum1 / Q80U78 / pumilio RNA-binding family member 1 / Q14671*  / complex
 ENSMUSG00000024661 Fth1 / P09528 / Ferritin heavy chain Ferritin heavy chain, N-terminally processed / P02794* / ferritin heavy chain 1*  / complex
 ENSMUSG00000050708 Ftl1 / FTL* / P02792* / ferritin light chain*  / complex
 ENSMUSG00000028082 Q91X43 / Sh3d19 / SH3 domain-containing protein 19 / Q5HYK7* / SH3 domain containing 19*  / complex
 ENSMUSG00000006169 Clint1 / Mus musculus clathrin interactor 1 (Clint1), transcript variant 2, mRNA. / Q14677* / clathrin interactor 1*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr