ENSG00000182264


Homo sapiens

Features
Gene ID: ENSG00000182264
  
Biological name :IZUMO1
  
Synonyms : IZUMO1 / izumo sperm-egg fusion 1 / Q8IYV9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.33
Gene start: 48740852
Gene end: 48746909
  
Corresponding Affymetrix probe sets: 1554196_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327786
Ensembl peptide - ENSP00000470144
Ensembl peptide - ENSP00000471134
Ensembl peptide - ENSP00000471815
NCBI entrez gene - 284359     See in Manteia.
OMIM - 609278
RefSeq - XM_017026646
RefSeq - NM_001321864
RefSeq - NM_001321865
RefSeq - NM_182575
RefSeq - XM_005258793
RefSeq - XM_011526811
RefSeq - XM_011526812
RefSeq - XM_011526813
RefSeq - XM_011526815
RefSeq Peptide - NP_001308793
RefSeq Peptide - NP_001308794
RefSeq Peptide - NP_872381
swissprot - Q8IYV9
swissprot - M0R0B8
Ensembl - ENSG00000182264
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 izumo1ENSDARG00000116848Danio rerio
 Izumo1ENSMUSG00000064158Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013783  Immunoglobulin-like fold
 IPR029389  Izumo sperm-egg fusion protein
 IPR032699  Izumo protein, immunoglobulin domain
 IPR032700  Izumo sperm-egg fusion protein 1
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IC
 biological_processGO:0007338 single fertilization ISS
 biological_processGO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization IDA
 biological_processGO:0034113 heterotypic cell-cell adhesion ISS
 biological_processGO:0035036 sperm-egg recognition IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0086080 protein binding involved in heterotypic cell-cell adhesion ISS


Pathways (from Reactome)
Pathway description
Sperm:Oocyte Membrane Binding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000010278 CD9 / P21926 / CD9 molecule  / complex / reaction






 

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