ENSG00000010278


Homo sapiens

Features
Gene ID: ENSG00000010278
  
Biological name :CD9
  
Synonyms : CD9 / CD9 molecule / P21926
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.31
Gene start: 6199715
Gene end: 6238271
  
Corresponding Affymetrix probe sets: 201005_at (Human Genome U133 Plus 2.0 Array)   233317_at (Human Genome U133 Plus 2.0 Array)   233322_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000493732
Ensembl peptide - ENSP00000494858
Ensembl peptide - ENSP00000496639
Ensembl peptide - ENSP00000495090
Ensembl peptide - ENSP00000009180
Ensembl peptide - ENSP00000371955
Ensembl peptide - ENSP00000371958
Ensembl peptide - ENSP00000371959
Ensembl peptide - ENSP00000440985
Ensembl peptide - ENSP00000478288
NCBI entrez gene - 928     See in Manteia.
OMIM - 143030
RefSeq - NM_001769
RefSeq - XM_011521040
RefSeq - XM_005253814
RefSeq Peptide - NP_001317241
RefSeq Peptide - NP_001760
swissprot - A6NNI4
swissprot - A0A087WU13
swissprot - P21926
swissprot - F5GXT1
swissprot - G8JLH6
Ensembl - ENSG00000010278
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd9aENSDARG00000005842Danio rerio
 cd9bENSDARG00000016691Danio rerio
 CD9ENSGALG00000017274Gallus gallus
 Cd9ENSMUSG00000030342Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60636 / TSPAN2 / tetraspanin 2ENSG0000013419846
CD81 / P60033 / CD81 moleculeENSG0000011065144
P19075 / TSPAN8 / tetraspanin 8ENSG0000012732434
Q96SJ8 / TSPAN18 / tetraspanin 18ENSG0000015757030
O75954 / TSPAN9 / tetraspanin 9ENSG0000001110529
CD82 / P27701 / CD82 moleculeENSG0000008511729
O14817 / TSPAN4 / tetraspanin 4ENSG0000021406326
CD53 / P19397 / CD53 moleculeENSG0000014311925
O60635 / TSPAN1 / tetraspanin 1ENSG0000011747225
CD37 / P11049 / CD37 moleculeENSG0000010489424
P0C672 / TSPAN19 / tetraspanin 19ENSG0000023173821


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009414 response to water deprivation IEA
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0030168 platelet activation NAS
 biological_processGO:0030913 paranodal junction assembly IBA
 biological_processGO:0031623 receptor internalization ISS
 biological_processGO:0051271 negative regulation of cellular component movement IDA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus ISS
 biological_processGO:0090331 negative regulation of platelet aggregation IDA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0030669 clathrin-coated endocytic vesicle membrane TAS
 cellular_componentGO:0031092 platelet alpha granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome IDA
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Platelet degranulation
Sperm:Oocyte Membrane Binding
Uptake and function of diphtheria toxin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000113070 HBEGF / Q99075 / heparin binding EGF like growth factor  / reaction / complex
 ENSG00000182264 IZUMO1 / Q8IYV9 / izumo sperm-egg fusion 1  / complex / reaction






 

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