ENSMUSG00000030342


Mus musculus

Features
Gene ID: ENSMUSG00000030342
  
Biological name :Cd9
  
Synonyms : Cd9 / CD9 antigen / P40240
  
Possible biological names infered from orthology : CD9 molecule / P21926
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F3
Gene start: 125460266
Gene end: 125494791
  
Corresponding Affymetrix probe sets: 10548030 (MoGene1.0st)   1416066_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032492
NCBI entrez gene - 12527     See in Manteia.
MGI - MGI:88348
RefSeq - NM_007657
RefSeq Peptide - NP_031683
swissprot - P40240
Ensembl - ENSMUSG00000030342
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd9aENSDARG00000005842Danio rerio
 cd9bENSDARG00000016691Danio rerio
 CD9ENSGALG00000017274Gallus gallus
 CD9ENSG00000010278Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q922J6 / Tspan2 / tetraspanin 2 / O60636*ENSMUSG0000002785848
Cd81 / P35762 / CD81 antigen / P60033* / CD81 molecule*ENSMUSG0000003770645
Q8R3G9 / Tspan8 / Tetraspanin-8 / P19075*ENSMUSG0000003412731
Q80WR1 / Tspan18 / Tetraspanin-18 / Q96SJ8*ENSMUSG0000002721729
Cd82 / P40237 / CD82 antigen / P27701* / CD82 molecule*ENSMUSG0000002721528
Q8BJU2 / Tspan9 / Mus musculus tetraspanin 9 (Tspan9), transcript variant 2, mRNA. / O75954* / tetraspanin 9*ENSMUSG0000003035228
Q9DCK3 / Tspan4 / tetraspanin 4 / O14817*ENSMUSG0000002551127
Q99J59 / Tspan1 / Tetraspanin-1 / O60635*ENSMUSG0000002869926
Cd37 / Q61470 / Leukocyte antigen CD37 / P11049* / CD37 molecule*ENSMUSG0000003079825
Cd53 / Q61451 / Leukocyte surface antigen CD53 / P19397* / CD53 molecule*ENSMUSG0000004074725


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization IDA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009414 response to water deprivation IEA
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0030913 paranodal junction assembly IDA
 biological_processGO:0031623 receptor internalization IDA
 biological_processGO:0051271 negative regulation of cellular component movement IEA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IDA
 biological_processGO:0090331 negative regulation of platelet aggregation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Platelet degranulation
Sperm:Oocyte Membrane Binding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cry1tm1Asn/Cry1tm1Asn,Cry2tm1Asn/Cry2tm1Asn,Pde6brd1/Pde6brd1
Genetic Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6

Allelic Composition: Cd9tm1Kudo/Cd9tm1Kudo
Genetic Background: involves: 129X1/SvJ * C57BL/6N

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Cry1tm1Asn/Cry1tm1Asn,Cry2tm1Asn/Cry2tm1Asn,Pde6brd1/Pde6brd1
Genetic Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Cd9tm1Kudo/Cd9tm1Kudo
Genetic Background: involves: 129X1/SvJ * C57BL/6N

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cry1tm1Asn/Cry1tm1Asn,Cry2tm1Asn/Cry2tm1Asn,Pde6brd1/Pde6brd1
Genetic Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0004984 increased osteoclast cell number "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd81tm1Tmiy/Cd81tm1Tmiy,Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008976 delayed female fertility "ability of a female organism to produce live offspring occurring at a later than expected age" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cry1tm1Asn/Cry1tm1Asn,Cry2tm1Asn/Cry2tm1Asn,Pde6brd1/Pde6brd1
Genetic Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000064158 Izumo1 / Q9D9J7 / Izumo sperm-egg fusion protein 1 / Q8IYV9* / izumo sperm-egg fusion 1*  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr