ENSMUSG00000037706


Mus musculus

Features
Gene ID: ENSMUSG00000037706
  
Biological name :Cd81
  
Synonyms : Cd81 / CD81 antigen / P35762
  
Possible biological names infered from orthology : CD81 molecule / P60033
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 143052739
Gene end: 143067934
  
Corresponding Affymetrix probe sets: 10559261 (MoGene1.0st)   1416330_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043768
Ensembl peptide - ENSMUSP00000147255
Ensembl peptide - ENSMUSP00000146533
NCBI entrez gene - 12520     See in Manteia.
MGI - MGI:1096398
RefSeq - NM_133655
RefSeq Peptide - NP_598416
swissprot - A0A140LJL0
swissprot - A0A140LHT1
swissprot - P35762
Ensembl - ENSMUSG00000037706
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cd81aENSDARG00000036080Danio rerio
 cd81bENSDARG00000022437Danio rerio
 CD81ENSGALG00000006546Gallus gallus
 CD81ENSG00000110651Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cd9 / P40240 / CD9 antigen / P21926* / CD9 molecule*ENSMUSG0000003034243
Q922J6 / Tspan2 / tetraspanin 2 / O60636*ENSMUSG0000002785841
Q8R3G9 / Tspan8 / Tetraspanin-8 / P19075*ENSMUSG0000003412729
Cd53 / Q61451 / Leukocyte surface antigen CD53 / P19397* / CD53 molecule*ENSMUSG0000004074727
Q99J59 / Tspan1 / Tetraspanin-1 / O60635*ENSMUSG0000002869926
Cd82 / P40237 / CD82 antigen / P27701* / CD82 molecule*ENSMUSG0000002721526
Q80WR1 / Tspan18 / Tetraspanin-18 / Q96SJ8*ENSMUSG0000002721726
Q8BJU2 / Tspan9 / Mus musculus tetraspanin 9 (Tspan9), transcript variant 2, mRNA. / O75954* / tetraspanin 9*ENSMUSG0000003035226
Q9DCK3 / Tspan4 / tetraspanin 4 / O14817*ENSMUSG0000002551123
Cd37 / Q61470 / Leukocyte antigen CD37 / P11049* / CD37 molecule*ENSMUSG0000003079822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0030307 positive regulation of cell growth TAS
 biological_processGO:0030890 positive regulation of B cell proliferation TAS
 biological_processGO:0031623 receptor internalization IDA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0061462 protein localization to lysosome IEA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IDA
 biological_processGO:1904352 positive regulation of protein catabolic process in the vacuole IEA
 biological_processGO:2000145 regulation of cell motility IGI
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:1990459 transferrin receptor binding IEA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0000136 abnormal microglial cell morphology "anomalous structure, number, or composition of the small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, J:71688]
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Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0000716 abnormal immune system cell morphology "anomalous structure, development, or number of immune cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0000780 abnormal corpus callosum morphology "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0000789 thickened cerebral cortex "Increased depth of the mantle coveringthe surface of the cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:49481]
Show

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
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Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0000952 abnormal CNS glia "anomalous structure, number or composition of non-neuronal cells of the central nervous system that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pik3cgtm1Dwu/Pik3cgtm1Dwu
Genetic Background: B6.Cg-Pik3cgtm1Dwu

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Mapk1tm1Melo/Mapk1+
Genetic Background: involves: 129S2/SvPas

 MP:0001805 decreased IgG "less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Faddtm1Wnt/Faddtm1Wnt,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0,Tg(Tcra2C,Tcrb2C)1Dlo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57L * CBA * ICR * SJL

 MP:0001906 increased dopamine level "greater than the normal concentration of this catecholamine neurotransmitter, dervied from tyrosine and the precursor to norepinephrine and epinephrine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Mapk1tm1Melo/Mapk1+
Genetic Background: involves: 129S2/SvPas

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0002144 abnormal B lymphocyte development "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0002176 high brain weight "greater than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

Allelic Composition: Cd81tm1Tmiy/Cd81tm1Tmiy,Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002494 increased IgM "greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Mapk1tm1Melo/Mapk1+
Genetic Background: involves: 129S2/SvPas

 MP:0002495 increased IgA "greater than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Mapk1tm1Melo/Mapk1+
Genetic Background: involves: 129S2/SvPas

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0004080 abnormal nucleus accumbens morphology "malformation in the group of neurons located at the head of the caudate nucleus and anterior to the putamen; these neurons normally are involved in sensations of pleasure and reactions to addictive substances " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Cd81tm1Geha/Cd81tm1Geha
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004939 abnormal B cell morphology "any structural anomaly of lymphocytes that expresses membrane-bound immunoglobulin complexes in the mature form, and differentiate into antibody-secreting plasma cells and memory cells upon interaction with antigen; B cells are the primary lymphocyte responsible for humoral immunity, and are most effective against extracellular pathogens" [CL:0000236, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd81tm1Geha/Cd81tm1Geha
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004978 decreased B-1 B cell number "reduced number of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

Allelic Composition: Cd81tm1Geha/Cd81tm1Geha
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004984 increased osteoclast cell number "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd81tm1Tmiy/Cd81tm1Tmiy,Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005026 decreased susceptibility to parasitic infection "reduced likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Faddtm1Wnt/Faddtm1Wnt,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0,Tg(Tcra2C,Tcrb2C)1Dlo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57L * CBA * ICR * SJL

 MP:0005093 impaired B cell proliferation "absent or reduced ability of B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0005094 abnormal T cell proliferation "anomaly in the clonal expansion of naive T cells" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

 MP:0005154 increased B cell proliferation "greater than the normal response by B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hnf1btm1Sce/Hnf1btm1Sce
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * DBA/2)

Allelic Composition: Cd81tm1Geha/Cd81tm1Geha
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005466 abnormal T helper 2 physiology "anomalous response of the subset of T helper cells that enhance humoral immunity and inhibit cell-mediated immune responses; these cells produce IL-4 and induce B cells to produce IgE and IgG1, while also supporting eosinophil and mast cell functions " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Faddtm1Wnt/Faddtm1Wnt,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0,Tg(Tcra2C,Tcrb2C)1Dlo/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57L * CBA * ICR * SJL

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: CByJ.129-Cd81tm1Lvy

 MP:0005597 decreased susceptibility to type I hypersensitivity reaction "less likelihood or resistance to developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks" [Pathology:ISBN 0-397-51047-0, J:68588, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: CByJ.129-Cd81tm1Lvy

 MP:0008168 decreased B-1a cell number "reduced number of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, PMID:11861604]
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Allelic Composition: Cd81tm1Geha/Cd81tm1Geha
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008263 abnormal hippocampus CA1 region morphology 
Show

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0008495 decreased IgG1 level "less than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008502 increased IgG3 level "greater than normal immunoglobulin class G3 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd81tm1Geha/Cd81tm1Geha
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009758 impaired behavioral response to cocaine "decreased sensitivity to cocaine resulting in a behavioral response, such as induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd81tm1Geha/Cd81tm1Geha
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009940 abnormal hippocampus pyramidal cell morphology "any structural anomaly of the projection neuron in the pyramidal layer of the hippocampus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0012065 increased astrocyte number "increase in the number of the large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord" [CL:0000127, MGI:csmith]
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Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

 MP:0020082 increased hippocampus volume "deviation from the average range of the hippocampus volume compared to normal" [GOC:NV]
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Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: CByJ.129-Cd81tm1Lvy

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NIHS-BC

Allelic Composition: Cd81tm1Lvy/Cd81tm1Lvy
Genetic Background: either: (B6ByJ.129-Cd81tm1Lvy x CByJ.129-Cd81tm1Lvy)F1 or (CByJ.129-Cd81tm1Lvy x B6ByJ.129-Cd81tm1Lvy)F1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030724 Cd19 / P25918 / Mus musculus CD19 antigen (Cd19), transcript variant 2, mRNA. / P15391* / CD19 molecule*  / complex
 ENSMUSG00000024164 C3 / P01027 / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acylation stimulating protein Complement C3b alpha chain Complement C3c alpha chain...  / reaction / complex






 

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