ENSG00000117472


Homo sapiens

Features
Gene ID: ENSG00000117472
  
Biological name :TSPAN1
  
Synonyms : O60635 / tetraspanin 1 / TSPAN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.1
Gene start: 46175073
Gene end: 46185958
  
Corresponding Affymetrix probe sets: 209114_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361072
NCBI entrez gene - 10103     See in Manteia.
OMIM - 613170
RefSeq - NM_005727
RefSeq - XM_011540460
RefSeq Peptide - NP_005718
swissprot - O60635
Ensembl - ENSG00000117472
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tspan1ENSDARG00000052027Danio rerio
 TSPAN1ENSGALG00000010343Gallus gallus
 Q99J59ENSMUSG00000028699Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96SJ8 / TSPAN18 / tetraspanin 18ENSG0000015757034
O75954 / TSPAN9 / tetraspanin 9ENSG0000001110528
P19075 / TSPAN8 / tetraspanin 8ENSG0000012732428
O14817 / TSPAN4 / tetraspanin 4ENSG0000021406327
CD37 / P11049 / CD37 moleculeENSG0000010489427
CD82 / P27701 / CD82 moleculeENSG0000008511727
O60636 / TSPAN2 / tetraspanin 2ENSG0000013419826
CD81 / P60033 / CD81 moleculeENSG0000011065124
CD9 / P21926 / CD9 moleculeENSG0000001027824
CD53 / P19397 / CD53 moleculeENSG0000014311923
P0C672 / TSPAN19 / tetraspanin 19ENSG0000023173818


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0045807 positive regulation of endocytosis IMP
 biological_processGO:0050821 protein stabilization IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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