ENSG00000134198


Homo sapiens

Features
Gene ID: ENSG00000134198
  
Biological name :TSPAN2
  
Synonyms : O60636 / tetraspanin 2 / TSPAN2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.2
Gene start: 115048011
Gene end: 115089500
  
Corresponding Affymetrix probe sets: 214606_at (Human Genome U133 Plus 2.0 Array)   227233_at (Human Genome U133 Plus 2.0 Array)   227236_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358529
Ensembl peptide - ENSP00000415256
Ensembl peptide - ENSP00000358528
NCBI entrez gene - 10100     See in Manteia.
OMIM - 613133
RefSeq - XM_016999996
RefSeq - NM_001308315
RefSeq - NM_001308316
RefSeq - NM_005725
RefSeq Peptide - NP_001295244
RefSeq Peptide - NP_001295245
RefSeq Peptide - NP_005716
swissprot - B1AKP1
swissprot - B1AKP2
swissprot - O60636
Ensembl - ENSG00000134198
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tspan2aENSDARG00000003754Danio rerio
 tspan2bENSDARG00000059202Danio rerio
 TSPAN2ENSGALG00000002554Gallus gallus
 Q922J6ENSMUSG00000027858Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD9 / P21926 / CD9 moleculeENSG0000001027848
CD81 / P60033 / CD81 moleculeENSG0000011065143
P19075 / TSPAN8 / tetraspanin 8ENSG0000012732429
O14817 / TSPAN4 / tetraspanin 4ENSG0000021406329
O60635 / TSPAN1 / tetraspanin 1ENSG0000011747229
O75954 / TSPAN9 / tetraspanin 9ENSG0000001110527
Q96SJ8 / TSPAN18 / tetraspanin 18ENSG0000015757027
CD82 / P27701 / CD82 moleculeENSG0000008511727
CD53 / P19397 / CD53 moleculeENSG0000014311926
CD37 / P11049 / CD37 moleculeENSG0000010489421
P0C672 / TSPAN19 / tetraspanin 19ENSG0000023173821


Protein motifs (from Interpro)
Interpro ID Name
 IPR000301  Tetraspanin
 IPR008952  Tetraspanin, EC2 domain superfamily
 IPR018499  Tetraspanin/Peripherin
 IPR018503  Tetraspanin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0014002 astrocyte development IEA
 biological_processGO:0014005 microglia development IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0061564 axon development IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr