ENSG00000184735


Homo sapiens

Features
Gene ID: ENSG00000184735
  
Biological name :DDX53
  
Synonyms : DDX53 / DEAD-box helicase 53 / Q86TM3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p22.11
Gene start: 22999961
Gene end: 23003589
  
Corresponding Affymetrix probe sets: 1555357_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368667
NCBI entrez gene - 168400     See in Manteia.
RefSeq - NM_182699
RefSeq Peptide - NP_874358
swissprot - Q86TM3
Ensembl - ENSG00000184735
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx43ENSDARG00000022614Danio rerio
 ENSGALG00000015928Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX43 / Q9NXZ2 / DEAD-box helicase 43ENSG0000008000761
DDX17 / Q92841 / DEAD-box helicase 17ENSG0000010020133
DDX5 / P17844 / DEAD-box helicase 5ENSG0000010865432
DDX42 / Q86XP3 / DEAD-box helicase 42ENSG0000019823128


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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