ENSG00000198231


Homo sapiens

Features
Gene ID: ENSG00000198231
  
Biological name :DDX42
  
Synonyms : DDX42 / DEAD-box helicase 42 / Q86XP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q23.3
Gene start: 63773603
Gene end: 63819317
  
Corresponding Affymetrix probe sets: 1559953_at (Human Genome U133 Plus 2.0 Array)   1559954_s_at (Human Genome U133 Plus 2.0 Array)   201788_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464050
Ensembl peptide - ENSP00000463561
Ensembl peptide - ENSP00000464232
Ensembl peptide - ENSP00000352308
Ensembl peptide - ENSP00000374574
Ensembl peptide - ENSP00000390121
Ensembl peptide - ENSP00000461957
Ensembl peptide - ENSP00000462174
Ensembl peptide - ENSP00000463038
NCBI entrez gene - 11325     See in Manteia.
OMIM - 613369
RefSeq - XM_017024112
RefSeq - NM_007372
RefSeq - NM_203499
RefSeq - XM_006721657
RefSeq - XM_011524259
RefSeq - XM_017024111
RefSeq Peptide - NP_987095
RefSeq Peptide - NP_031398
swissprot - J3KRV0
swissprot - J3KTK9
swissprot - J3QRI2
swissprot - A0A0A0MSJ0
swissprot - Q86XP3
swissprot - J3KRE3
Ensembl - ENSG00000198231
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx42ENSDARG00000037928Danio rerio
 DDX42ENSGALG00000000581Gallus gallus
 Ddx42ENSMUSG00000020705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX17 / Q92841 / DEAD-box helicase 17ENSG0000010020125
DDX5 / P17844 / DEAD-box helicase 5ENSG0000010865424
DDX43 / Q9NXZ2 / DEAD-box helicase 43ENSG0000008000721
DDX53 / Q86TM3 / DEAD-box helicase 53ENSG0000018473519


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0008104 protein localization IDA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0042981 regulation of apoptotic process IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr