ENSMUSG00000020705


Mus musculus

Features
Gene ID: ENSMUSG00000020705
  
Biological name :Ddx42
  
Synonyms : ATP-dependent RNA helicase DDX42 / Ddx42 / Q810A7
  
Possible biological names infered from orthology : DEAD-box helicase 42 / Q86XP3
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E1
Gene start: 106216926
Gene end: 106249139
  
Corresponding Affymetrix probe sets: 10382049 (MoGene1.0st)   1427022_at (Mouse Genome 430 2.0 Array)   1443719_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021046
NCBI entrez gene - 72047     See in Manteia.
MGI - MGI:1919297
RefSeq - XM_017314780
RefSeq - NM_028074
RefSeq - XM_017314779
RefSeq Peptide - NP_082350
swissprot - Q810A7
Ensembl - ENSMUSG00000020705
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx42ENSDARG00000037928Danio rerio
 DDX42ENSGALG00000000581Gallus gallus
 DDX42ENSG00000198231Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ddx17 / Q501J6 / Probable ATP-dependent RNA helicase DDX17 / Q92841* / DEAD-box helicase 17*ENSMUSG0000005506525
Ddx5 / Mus musculus DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (Ddx5), transcript variant 3, mRNA. / P17844* / DEAD-box helicase 5*ENSMUSG0000002071924
Ddx43 / DEAD-box helicase 43 / Q9NXZ2*ENSMUSG0000007029121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0042981 regulation of apoptotic process IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008347 decreased gamma-delta T cell number "reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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