ENSG00000185658


Homo sapiens

Features
Gene ID: ENSG00000185658
  
Biological name :BRWD1
  
Synonyms : bromodomain and WD repeat domain containing 1 / BRWD1 / Q9NSI6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.2
Gene start: 39184176
Gene end: 39321559
  
Corresponding Affymetrix probe sets: 1553227_s_at (Human Genome U133 Plus 2.0 Array)   214820_at (Human Genome U133 Plus 2.0 Array)   219280_at (Human Genome U133 Plus 2.0 Array)   225446_at (Human Genome U133 Plus 2.0 Array)   231860_at (Human Genome U133 Plus 2.0 Array)   231960_at (Human Genome U133 Plus 2.0 Array)   238890_at (Human Genome U133 Plus 2.0 Array)   244622_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415066
Ensembl peptide - ENSP00000395575
Ensembl peptide - ENSP00000398900
Ensembl peptide - ENSP00000330753
Ensembl peptide - ENSP00000342106
Ensembl peptide - ENSP00000344333
Ensembl peptide - ENSP00000370178
Ensembl peptide - ENSP00000389882
Ensembl peptide - ENSP00000390684
Ensembl peptide - ENSP00000391014
Ensembl peptide - ENSP00000393702
NCBI entrez gene - 54014     See in Manteia.
OMIM - 617824
RefSeq - XM_017028375
RefSeq - NM_001007246
RefSeq - NM_018963
RefSeq - NM_033656
RefSeq - XM_011529611
RefSeq - XM_011529612
RefSeq - XM_011529613
RefSeq - XM_017028373
RefSeq - XM_017028374
RefSeq Peptide - NP_061836
RefSeq Peptide - NP_387505
RefSeq Peptide - NP_001007247
swissprot - H0Y500
swissprot - H0Y5I9
swissprot - H7BZR9
swissprot - H7C409
swissprot - H0Y463
swissprot - Q9NSI6
swissprot - H0Y4A7
swissprot - H0Y4R9
Ensembl - ENSG00000185658
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brwd1ENSDARG00000074747Danio rerio
 BRWD1ENSGALG00000016065Gallus gallus
 Brwd1ENSMUSG00000022914Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BRWD3 / Q6RI45 / bromodomain and WD repeat domain containing 3ENSG0000016528843
PHIP / Q8WWQ0 / pleckstrin homology domain interacting proteinENSG0000014624741


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR018359  Bromodomain, conserved site
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007010 cytoskeleton organization IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0038111 interleukin-7-mediated signaling pathway TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-7 signaling
Chromatin modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000127616 P51532 / SMARCA4 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4  / complex / reaction
 ENSG00000275714 P68431 / HIST1H3A / histone cluster 1 H3 family member a  / complex / reaction
 ENSG00000183598 Q71DI3 / HIST2H3D / histone cluster 2 H3 family member d  / complex / reaction






 

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