ENSG00000185722


Homo sapiens

Features
Gene ID: ENSG00000185722
  
Biological name :ANKFY1
  
Synonyms : ANKFY1 / ankyrin repeat and FYVE domain containing 1 / Q9P2R3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 4163907
Gene end: 4263977
  
Corresponding Affymetrix probe sets: 1562495_at (Human Genome U133 Plus 2.0 Array)   219868_s_at (Human Genome U133 Plus 2.0 Array)   224900_at (Human Genome U133 Plus 2.0 Array)   239073_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467522
Ensembl peptide - ENSP00000459943
Ensembl peptide - ENSP00000460619
Ensembl peptide - ENSP00000343362
Ensembl peptide - ENSP00000459247
Ensembl peptide - ENSP00000459775
NCBI entrez gene - 51479     See in Manteia.
OMIM - 607927
RefSeq - XM_017024733
RefSeq - NM_001257999
RefSeq - NM_001330063
RefSeq - NM_016376
RefSeq - XM_005256679
RefSeq - XM_011523926
RefSeq - XM_011523928
RefSeq - XM_011523933
RefSeq Peptide - NP_057460
RefSeq Peptide - NP_001244928
RefSeq Peptide - NP_001316992
swissprot - I3L1Z9
swissprot - Q9P2R3
swissprot - K7EPT2
swissprot - I3L3P8
Ensembl - ENSG00000185722
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ankfy1ENSDARG00000061013Danio rerio
 ANKFY1ENSGALG00000001467Gallus gallus
 Ankfy1ENSMUSG00000020790Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HGS / O14964 / hepatocyte growth factor-regulated tyrosine kinase substrateENSG0000018535911


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR000306  FYVE zinc finger
 IPR002110  Ankyrin repeat
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0016197 endosomal transport IMP
 biological_processGO:0034058 endosomal vesicle fusion IDA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:0048549 positive regulation of pinocytosis IDA
 biological_processGO:0090160 Golgi to lysosome transport IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030904 retromer complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0044354 macropinosome IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1901981 phosphatidylinositol phosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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