ENSMUSG00000020790


Mus musculus

Features
Gene ID: ENSMUSG00000020790
  
Biological name :Ankfy1
  
Synonyms : Ankfy1 / Q810B6 / Rabankyrin-5
  
Possible biological names infered from orthology : ankyrin repeat and FYVE domain containing 1 / Q9P2R3
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B4
Gene start: 72690006
Gene end: 72772146
  
Corresponding Affymetrix probe sets: 10378126 (MoGene1.0st)   1417685_at (Mouse Genome 430 2.0 Array)   1443654_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118252
Ensembl peptide - ENSMUSP00000118751
NCBI entrez gene - 11736     See in Manteia.
MGI - MGI:1337008
RefSeq - XM_006532039
RefSeq - NM_009671
RefSeq Peptide - NP_033801
swissprot - Q810B6
Ensembl - ENSMUSG00000020790
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ankfy1ENSDARG00000061013Danio rerio
 ANKFY1ENSGALG00000001467Gallus gallus
 ANKFY1ENSG00000185722Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hgs / hepatocyte growth factor-regulated tyrosine kinase substrate isoform 2 / O14964* / hepatocyte growth factor-regulated tyrosine kinase substrate*ENSMUSG0000011604512
Hgs / O14964* / hepatocyte growth factor-regulated tyrosine kinase substrate*ENSMUSG0000002579311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR000306  FYVE zinc finger
 IPR002110  Ankyrin repeat
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis NAS
 biological_processGO:0016197 endosomal transport IEA
 biological_processGO:0034058 endosomal vesicle fusion IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IEA
 biological_processGO:0048549 positive regulation of pinocytosis IEA
 biological_processGO:0090160 Golgi to lysosome transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0030904 retromer complex IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0044354 macropinosome IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1901981 phosphatidylinositol phosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: PrkdcM11Btlr/Prkdc+
Genetic Background: C57BL/6J-PrkdcM11Btlr

Allelic Composition: Ankfy1Gt(RRE069)Byg/Ankfy1Gt(RRE069)Byg
Genetic Background: C.129P2(B6)-Ankfy1Gt(RRE069)Byg

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: PrkdcM10Btlr/Prkdc+
Genetic Background: C57BL/6J-PrkdcM10Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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