ENSG00000185873


Homo sapiens

Features
Gene ID: ENSG00000185873
  
Biological name :TMPRSS11B
  
Synonyms : Q86T26 / TMPRSS11B / transmembrane serine protease 11B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q13.2
Gene start: 68226653
Gene end: 68245720
  
Corresponding Affymetrix probe sets: 1560712_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000330475
NCBI entrez gene - 132724     See in Manteia.
RefSeq - XM_011531608
RefSeq - NM_182502
RefSeq - XM_011531609
RefSeq Peptide - NP_872308
swissprot - Q86T26
Ensembl - ENSG00000185873
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q14C59ENSMUSG00000035861Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZWK6 / TMPRSS11F / transmembrane serine protease 11FENSG0000019809240
Q6ZMR5 / TMPRSS11A / transmembrane serine protease 11AENSG0000018705439
Q9UL52 / TMPRSS11E / transmembrane serine protease 11EENSG0000008712839
O60235 / TMPRSS11D / transmembrane serine protease 11DENSG0000015380238
ACR / P10323 / acrosinENSG0000010031227
CFI / P05156 / complement factor IENSG0000020540325
P0CW18 / PRSS56 / serine protease 56ENSG0000023741224
Q86WS5 / TMPRSS12 / transmembrane serine protease 12ENSG0000018645222
AC126283.2ENSG0000028533020


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR017329  Peptidase S1A, HAT/DESC1
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR036364  SEA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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