ENSG00000186452


Homo sapiens

Features
Gene ID: ENSG00000186452
  
Biological name :TMPRSS12
  
Synonyms : Q86WS5 / TMPRSS12 / transmembrane serine protease 12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.12
Gene start: 50842920
Gene end: 50887884
  
Corresponding Affymetrix probe sets: 1569176_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381476
Ensembl peptide - ENSP00000447259
NCBI entrez gene - 283471     See in Manteia.
RefSeq - NM_182559
RefSeq Peptide - NP_872365
swissprot - F8WBX2
swissprot - Q86WS5
Ensembl - ENSG00000186452
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmprss12ENSDARG00000093100Danio rerio
 TMPRSS12ENSGALG00000036550Gallus gallus
 Q3V0Q7ENSMUSG00000045631Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P0CW18 / PRSS56 / serine protease 56ENSG0000023741230
Q6ZWK6 / TMPRSS11F / transmembrane serine protease 11FENSG0000019809230
ACR / P10323 / acrosinENSG0000010031230
Q6ZMR5 / TMPRSS11A / transmembrane serine protease 11AENSG0000018705429
O60235 / TMPRSS11D / transmembrane serine protease 11DENSG0000015380228
CFI / P05156 / complement factor IENSG0000020540327
Q9UL52 / TMPRSS11E / transmembrane serine protease 11EENSG0000008712827
Q86T26 / TMPRSS11B / transmembrane serine protease 11BENSG0000018587326
AC126283.2ENSG0000028533022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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