ENSG00000185883


Homo sapiens

Features
Gene ID: ENSG00000185883
  
Biological name :ATP6V0C
  
Synonyms : ATP6V0C / ATPase H+ transporting V0 subunit c / P27449
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 2513870
Gene end: 2520218
  
Corresponding Affymetrix probe sets: 200954_at (Human Genome U133 Plus 2.0 Array)   36994_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000329757
Ensembl peptide - ENSP00000454597
Ensembl peptide - ENSP00000454868
Ensembl peptide - ENSP00000457782
NCBI entrez gene - 527     See in Manteia.
OMIM - 108745
RefSeq - NM_001694
RefSeq - NM_001198569
RefSeq Peptide - NP_001185498
RefSeq Peptide - NP_001685
swissprot - P27449
swissprot - H3BMY0
swissprot - H3BNI4
Ensembl - ENSG00000185883
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp6v0caENSDARG00000057853Danio rerio
 atp6v0cbENSDARG00000036577Danio rerio
 ATP6V0CENSGALG00000009229Gallus gallus
 P63082ENSMUSG00000024121Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000245  V-ATPase proteolipid subunit
 IPR002379  V-ATPase proteolipid subunit C-like domain
 IPR011555  V-ATPase proteolipid subunit C, eukaryotic
 IPR035921  F/V-ATP synthase subunit C superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007042 lysosomal lumen acidification IBA
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016241 regulation of macroautophagy NAS
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IMP
 biological_processGO:0033572 transferrin transport TAS
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0090383 phagosome acidification TAS
 biological_processGO:1902600 proton transmembrane transport TAS
 cellular_componentGO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain IBA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005773 vacuole IEA
 cellular_componentGO:0005774 vacuolar membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane TAS
 cellular_componentGO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain IEA
 cellular_componentGO:0033179 proton-transporting V-type ATPase, V0 domain IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0046933 proton-transporting ATP synthase activity, rotational mechanism TAS
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism TAS


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Neutrophil degranulation
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000185883 P27449 / ATP6V0C / ATPase H+ transporting V0 subunit c  / complex






 

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