ENSG00000185896


Homo sapiens

Features
Gene ID: ENSG00000185896
  
Biological name :LAMP1
  
Synonyms : LAMP1 / lysosomal associated membrane protein 1 / P11279
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q34
Gene start: 113297241
Gene end: 113323672
  
Corresponding Affymetrix probe sets: 201551_s_at (Human Genome U133 Plus 2.0 Array)   201552_at (Human Genome U133 Plus 2.0 Array)   201553_s_at (Human Genome U133 Plus 2.0 Array)   213728_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333298
NCBI entrez gene - 3916     See in Manteia.
OMIM - 153330
RefSeq - XM_011537494
RefSeq - NM_005561
RefSeq Peptide - NP_005552
swissprot - P11279
swissprot - A0A024RDY3
Ensembl - ENSG00000185896
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lamp1ENSDARG00000092610Danio rerio
 LAMP1ENSDARG00000100181Danio rerio
 LAMP1ENSGALG00000037697Gallus gallus
 Lamp1ENSMUSG00000031447Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LAMP2 / P13473 / lysosomal associated membrane protein 2ENSG0000000589334
CD68 / P34810 / CD68 moleculeENSG0000012922621
LAMP3 / Q9UQV4 / lysosomal associated membrane protein 3ENSG0000007808119


Protein motifs (from Interpro)
Interpro ID Name
 IPR002000  Lysosome-associated membrane glycoprotein
 IPR018134  Lysosome-associated membrane glycoprotein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008626 granzyme-mediated apoptotic signaling pathway IMP
 biological_processGO:0016032 viral process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043323 positive regulation of natural killer cell degranulation IMP
 biological_processGO:0045954 positive regulation of natural killer cell mediated cytotoxicity IMP
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0048102 autophagic cell death IEA
 biological_processGO:0050821 protein stabilization ISS
 biological_processGO:0072594 establishment of protein localization to organelle IMP
 biological_processGO:0090160 Golgi to lysosome transport IMP
 biological_processGO:1902513 regulation of organelle transport along microtubule IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome TAS
 cellular_componentGO:0005765 lysosomal membrane ISS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005771 multivesicular body IEA
 cellular_componentGO:0005773 vacuole IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0010008 endosome membrane ISS
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0044194 cytolytic granule IEA
 cellular_componentGO:0044754 autolysosome IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IMP
 cellular_componentGO:0061474 phagolysosome membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097208 alveolar lamellar body IEA
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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