ENSG00000186795


Homo sapiens

Features
Gene ID: ENSG00000186795
  
Biological name :KCNK18
  
Synonyms : KCNK18 / potassium two pore domain channel subfamily K member 18 / Q7Z418
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q25.3
Gene start: 117197489
Gene end: 117210299
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000334650
NCBI entrez gene - 338567     See in Manteia.
OMIM - 613655
RefSeq - NM_181840
RefSeq Peptide - NP_862823
swissprot - Q7Z418
Ensembl - ENSG00000186795
  
Related genetic diseases (OMIM): 613656 - {Migraine, with or without aura, susceptibility to, 13}, 613656
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnk18ENSDARG00000057049Danio rerio
 KCNK18ENSGALG00000009265Gallus gallus
 Kcnk18ENSMUSG00000040901Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003280  Two pore domain potassium channel
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0071435 potassium ion export IDA
 biological_processGO:0071467 cellular response to pH IDA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IC
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005267 potassium channel activity TAS
 molecular_functionGO:0015269 calcium-activated potassium channel activity IEA
 molecular_functionGO:0015271 outward rectifier potassium channel activity IDA
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
TWIK-related spinal cord K+ channel (TRESK)
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000186795 KCNK18 / Q7Z418 / potassium two pore domain channel subfamily K member 18  / complex






 

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