ENSG00000187513


Homo sapiens

Features
Gene ID: ENSG00000187513
  
Biological name :GJA4
  
Synonyms : gap junction protein alpha 4 / GJA4 / P35212
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.3
Gene start: 34792998
Gene end: 34795747
  
Corresponding Affymetrix probe sets: 204904_at (Human Genome U133 Plus 2.0 Array)   40687_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000343676
Ensembl peptide - ENSP00000409186
NCBI entrez gene - 2701     See in Manteia.
OMIM - 121012
RefSeq - XM_017001043
RefSeq - NM_002060
RefSeq - XM_005270750
RefSeq Peptide - NP_002051
swissprot - Q5JW71
swissprot - P35212
Ensembl - ENSG00000187513
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cx39.4ENSDARG00000070357Danio rerio
 GJA4ENSGALG00000002532Gallus gallus
 Gja4ENSMUSG00000050234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GJA1 / P17302 / gap junction protein alpha 1ENSG0000015266147
GJA3 / Q9Y6H8 / gap junction protein alpha 3ENSG0000012174345
GJA8 / P48165 / gap junction protein alpha 8ENSG0000012163443
GJA5 / P36382 / gap junction protein alpha 5ENSG0000026510743
GJA9 / P57773 / gap junction protein alpha 9ENSG0000013123341
GJA10 / Q969M2 / gap junction protein alpha 10ENSG0000013535540
GJC2 / Q5T442 / gap junction protein gamma 2ENSG0000019883537
GJC1 / P36383 / gap junction protein gamma 1ENSG0000018296336
GJD2 / Q9UKL4 / gap junction protein delta 2ENSG0000015924833
GJD3 / Q8N144 / gap junction protein delta 3ENSG0000018315330


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR002263  Gap junction alpha-4 protein (Cx37)
 IPR013092  Connexin, N-terminal
 IPR017990  Connexin, conserved site
 IPR019570  Gap junction protein, cysteine-rich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0003158 endothelium development IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007043 cell-cell junction assembly TAS
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0048265 response to pain IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005922 connexin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Gap junction assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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