ENSG00000187531


Homo sapiens

Features
Gene ID: ENSG00000187531
  
Biological name :SIRT7
  
Synonyms : Q9NRC8 / SIRT7 / sirtuin 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.3
Gene start: 81911939
Gene end: 81921323
  
Corresponding Affymetrix probe sets: 218797_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000329466
Ensembl peptide - ENSP00000459524
Ensembl peptide - ENSP00000461044
NCBI entrez gene - 51547     See in Manteia.
OMIM - 606212
RefSeq - XM_011523581
RefSeq - NM_016538
RefSeq - XM_006722284
RefSeq - XM_011523580
RefSeq Peptide - NP_057622
swissprot - Q9NRC8
swissprot - I3L480
swissprot - I3L2A4
Ensembl - ENSG00000187531
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sirt7ENSDARG00000060645Danio rerio
 SIRT7ENSGALG00000007286Gallus gallus
 Sirt7ENSMUSG00000025138Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIRT6 / Q8N6T7 / sirtuin 6ENSG0000007746331


Protein motifs (from Interpro)
Interpro ID Name
 IPR003000  Sirtuin family
 IPR026590  Sirtuin family, catalytic core domain
 IPR029035  DHS-like NAD/FAD-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007072 positive regulation of transcription involved in exit from mitosis IMP
 biological_processGO:0009303 rRNA transcription IMP
 biological_processGO:0070932 histone H3 deacetylation IDA
 biological_processGO:0070933 histone H4 deacetylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005731 nucleolus organizer region IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070403 NAD+ binding IEA
 molecular_functionGO:0097372 NAD-dependent histone deacetylase activity (H3-K18 specific) IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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