ENSG00000187550


Homo sapiens

Features
Gene ID: ENSG00000187550
  
Biological name :SBK2
  
Synonyms : P0C263 / SBK2 / SH3 domain binding kinase family member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.42
Gene start: 55529733
Gene end: 55537089
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000345044
Ensembl peptide - ENSP00000389015
NCBI entrez gene - 646643     See in Manteia.
RefSeq - NM_001101401
RefSeq - XM_006723327
RefSeq Peptide - NP_001094871
swissprot - P0C263
Ensembl - ENSG00000187550
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-8e10.3ENSDARG00000058944Danio rerio
 SBK2ENSGALG00000013035Gallus gallus
 Sbk2ENSMUSG00000030433Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SBK3 / P0C264 / SH3 domain binding kinase family member 3ENSG0000023127438
SBK1 / Q52WX2 / SH3 domain binding kinase 1ENSG0000018832236
CHEK1 / O14757 / checkpoint kinase 1ENSG0000014955417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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