ENSMUSG00000030433


Mus musculus

Features
Gene ID: ENSMUSG00000030433
  
Biological name :Sbk2
  
Synonyms : P0C5K1 / Sbk2 / Serine/threonine-protein kinase SBK2
  
Possible biological names infered from orthology : P0C263 / SH3 domain binding kinase family member 2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A1
Gene start: 4940512
Gene end: 4964406
  
Corresponding Affymetrix probe sets: 10559694 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000146819
Ensembl peptide - ENSMUSP00000032598
Ensembl peptide - ENSMUSP00000138187
Ensembl peptide - ENSMUSP00000138504
NCBI entrez gene - 381836     See in Manteia.
MGI - MGI:2685925
RefSeq - XM_006540138
RefSeq - XM_006540139
RefSeq - NM_001146329
RefSeq Peptide - NP_001139801
swissprot - P0C5K1
swissprot - A0A140LIH2
swissprot - S4R1E6
Ensembl - ENSMUSG00000030433
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-8e10.3ENSDARG00000058944Danio rerio
 SBK2ENSGALG00000013035Gallus gallus
 SBK2ENSG00000187550Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sbk1 / Q8QZX0 / Serine/threonine-protein kinase SBK1 / Q52WX2* / SH3 domain binding kinase 1*ENSMUSG0000004297835
Sbk3 / P0C5K0 / Uncharacterized serine/threonine-protein kinase SBK3 / P0C264* / SH3 domain binding kinase family member 3*ENSMUSG0000008527235
Chek1 / O35280 / Serine/threonine-protein kinase Chk1 / O14757* / checkpoint kinase 1*ENSMUSG0000003211322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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