ENSG00000187778


Homo sapiens

Features
Gene ID: ENSG00000187778
  
Biological name :MCRS1
  
Synonyms : MCRS1 / microspherule protein 1 / Q96EZ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.12
Gene start: 49556544
Gene end: 49568153
  
Corresponding Affymetrix probe sets: 202556_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449343
Ensembl peptide - ENSP00000448947
Ensembl peptide - ENSP00000450352
Ensembl peptide - ENSP00000345358
Ensembl peptide - ENSP00000349640
Ensembl peptide - ENSP00000444982
Ensembl peptide - ENSP00000447514
Ensembl peptide - ENSP00000447592
Ensembl peptide - ENSP00000447739
Ensembl peptide - ENSP00000448056
Ensembl peptide - ENSP00000448700
NCBI entrez gene - 10445     See in Manteia.
OMIM - 609504
RefSeq - XM_017018690
RefSeq - NM_001012300
RefSeq - NM_001278341
RefSeq - NM_006337
RefSeq - XM_005268572
RefSeq - XM_011537760
RefSeq - XM_017018689
RefSeq Peptide - NP_006328
RefSeq Peptide - NP_001012300
RefSeq Peptide - NP_001265270
swissprot - F8VP44
swissprot - F8VVA6
swissprot - F8VZC2
swissprot - F8W0I9
swissprot - F8W126
swissprot - H0YIA0
swissprot - H0YI67
swissprot - Q96EZ8
swissprot - A0A024R134
Ensembl - ENSG00000187778
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcrs1ENSDARG00000020840Danio rerio
 Mcrs1ENSMUSG00000037570Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR008984  SMAD/FHA domain superfamily
 IPR025999  Microspherule protein, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0043981 histone H4-K5 acetylation IDA
 biological_processGO:0043982 histone H4-K8 acetylation IDA
 biological_processGO:0043984 histone H4-K16 acetylation IDA
 biological_processGO:1904751 positive regulation of protein localization to nucleolus IDA
 cellular_componentGO:0000123 histone acetyltransferase complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005844 polysome ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031011 Ino80 complex IDA
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0071339 MLL1 complex IDA
 molecular_functionGO:0002151 G-quadruplex RNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008266 poly(U) RNA binding IDA
 molecular_functionGO:0034046 poly(G) binding IDA
 molecular_functionGO:0043995 histone acetyltransferase activity (H4-K5 specific) IDA
 molecular_functionGO:0043996 histone acetyltransferase activity (H4-K8 specific) IDA
 molecular_functionGO:0046972 histone acetyltransferase activity (H4-K16 specific) IDA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
UCH proteinases
DNA Damage Recognition in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr