ENSG00000187838


Homo sapiens

Features
Gene ID: ENSG00000187838
  
Biological name :PLSCR3
  
Synonyms : phospholipid scramblase 3 / PLSCR3 / Q9NRY6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7389727
Gene end: 7394843
  
Corresponding Affymetrix probe sets: 218828_at (Human Genome U133 Plus 2.0 Array)   56197_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461843
Ensembl peptide - ENSP00000483743
Ensembl peptide - ENSP00000316021
Ensembl peptide - ENSP00000438547
Ensembl peptide - ENSP00000458596
Ensembl peptide - ENSP00000458988
Ensembl peptide - ENSP00000459019
Ensembl peptide - ENSP00000459122
Ensembl peptide - ENSP00000459419
Ensembl peptide - ENSP00000460800
Ensembl peptide - ENSP00000461205
NCBI entrez gene - 57048     See in Manteia.
OMIM - 607611
RefSeq - NM_020360
RefSeq - NM_001201576
RefSeq Peptide - NP_001188505
RefSeq Peptide - NP_065093
swissprot - I3L4F5
swissprot - I3NI29
swissprot - Q8WYZ0
swissprot - Q9NRY6
swissprot - I3L161
swissprot - I3L1P6
swissprot - I3L1V1
swissprot - I3L3X5
Ensembl - ENSG00000187838
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plscr3aENSDARG00000093078Danio rerio
 plscr3bENSDARG00000069432Danio rerio
 si:dkey-62k3.6ENSDARG00000091614Danio rerio
 Plscr3ENSMUSG00000019461Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15162 / PLSCR1 / phospholipid scramblase 1ENSG0000018831351
PLSCR2 / Q9NRY7 / phospholipid scramblase 2ENSG0000016374644
A0PG75 / PLSCR5 / phospholipid scramblase family member 5ENSG0000023121340
PLSCR4 / Q9NRQ2 / phospholipid scramblase 4ENSG0000011469838


Protein motifs (from Interpro)
Interpro ID Name
 IPR005552  Scramblase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0017121 phospholipid scrambling NAS
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0005509 calcium ion binding NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0017128 phospholipid scramblase activity NAS
 molecular_functionGO:0048306 calcium-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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