ENSG00000188338


Homo sapiens

Features
Gene ID: ENSG00000188338
  
Biological name :SLC38A3
  
Synonyms : Q99624 / SLC38A3 / solute carrier family 38 member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.31
Gene start: 50205246
Gene end: 50221486
  
Corresponding Affymetrix probe sets: 205972_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479737
Ensembl peptide - ENSP00000484379
Ensembl peptide - ENSP00000483959
Ensembl peptide - ENSP00000481301
Ensembl peptide - ENSP00000480466
NCBI entrez gene - 10991     See in Manteia.
OMIM - 604437
RefSeq - XM_006712954
RefSeq - NM_006841
RefSeq Peptide - NP_006832
swissprot - A0A087WVW8
swissprot - A0A087X175
swissprot - A0A087X1Q4
swissprot - Q99624
swissprot - A0A087WWS5
Ensembl - ENSG00000188338
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc38a3aENSDARG00000027065Danio rerio
 slc38a3bENSDARG00000091061Danio rerio
 SLC38A3ENSGALG00000028871Gallus gallus
 Q9DCP2ENSMUSG00000010064Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WUX1 / SLC38A5 / solute carrier family 38 member 5ENSG0000001748357
Q969I6 / SLC38A4 / solute carrier family 38 member 4ENSG0000013920954
Q96QD8 / SLC38A2 / solute carrier family 38 member 2ENSG0000013429453
Q9H2H9 / SLC38A1 / solute carrier family 38 member 1ENSG0000011137146
Q8IZM9 / SLC38A6 / solute carrier family 38 member 6ENSG0000013997441
Q08AI6 / SLC38A11 / solute carrier family 38 member 11ENSG0000016950720
Q9HBR0 / SLC38A10 / solute carrier family 38 member 10ENSG0000015763719


Protein motifs (from Interpro)
Interpro ID Name
 IPR013057  Amino acid transporter, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003333 amino acid transmembrane transport IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006865 amino acid transport TAS
 biological_processGO:0006867 asparagine transport IDA
 biological_processGO:0006868 glutamine transport IDA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0015808 L-alanine transport IDA
 biological_processGO:0015817 histidine transport IDA
 biological_processGO:0051365 cellular response to potassium ion starvation IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH IEA
 biological_processGO:0089709 L-histidine transmembrane transport IEA
 biological_processGO:2000487 positive regulation of glutamine transport IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 molecular_functionGO:0005290 L-histidine transmembrane transporter activity IDA
 molecular_functionGO:0015171 amino acid transmembrane transporter activity TAS
 molecular_functionGO:0015180 L-alanine transmembrane transporter activity IDA
 molecular_functionGO:0015182 L-asparagine transmembrane transporter activity IDA
 molecular_functionGO:0015186 L-glutamine transmembrane transporter activity IDA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0015297 antiporter activity IEA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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