ENSG00000188566


Homo sapiens

Features
Gene ID: ENSG00000188566
  
Biological name :NDOR1
  
Synonyms : NADPH dependent diflavin oxidoreductase 1 / NDOR1 / Q9UHB4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.3
Gene start: 137205685
Gene end: 137217009
  
Corresponding Affymetrix probe sets: 219899_x_at (Human Genome U133 Plus 2.0 Array)   234318_x_at (Human Genome U133 Plus 2.0 Array)   234935_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000343344
Ensembl peptide - ENSP00000360576
Ensembl peptide - ENSP00000389905
Ensembl peptide - ENSP00000394309
NCBI entrez gene - 27158     See in Manteia.
OMIM - 606073
RefSeq - XM_017014627
RefSeq - NM_001144026
RefSeq - NM_001144027
RefSeq - NM_001144028
RefSeq - NM_014434
RefSeq - XM_011518545
RefSeq - XM_011518547
RefSeq - XM_011518548
RefSeq - XM_017014626
RefSeq Peptide - NP_001137498
RefSeq Peptide - NP_001137499
RefSeq Peptide - NP_001137500
RefSeq Peptide - NP_055249
swissprot - Q9UHB4
Ensembl - ENSG00000188566
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndor1ENSDARG00000007429Danio rerio
 NDOR1ENSGALG00000008920Gallus gallus
 AL732309.2ENSMUSG00000115074Mus musculus
 Ndor1ENSMUSG00000006471Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTRR / Q9UBK8 / 5-methyltetrahydrofolate-homocysteine methyltransferase reductaseENSG0000012427528


Protein motifs (from Interpro)
Interpro ID Name
 IPR001094  Flavodoxin-like
 IPR001433  Oxidoreductase FAD/NAD(P)-binding
 IPR001709  Flavoprotein pyridine nucleotide cytochrome reductase
 IPR003097  FAD-binding, type 1
 IPR008254  Flavodoxin/nitric oxide synthase
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel
 IPR028879  NADPH-dependent diflavin oxidoreductase 1
 IPR029039  Flavoprotein-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008219 cell death IDA
 biological_processGO:0036245 cellular response to menadione IDA
 biological_processGO:0055114 oxidation-reduction process IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003958 NADPH-hemoprotein reductase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0010181 FMN binding IDA
 molecular_functionGO:0016491 oxidoreductase activity IDA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IDA
 molecular_functionGO:0050661 NADP binding IDA


Pathways (from Reactome)
Pathway description
Cytosolic iron-sulfur cluster assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000005194 Q6FI81 / CIAPIN1 / cytokine induced apoptosis inhibitor 1  / complex






 

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