ENSG00000196104


Homo sapiens

Features
Gene ID: ENSG00000196104
  
Biological name :SPOCK3
  
Synonyms : Q9BQ16 / SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 / SPOCK3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q32.3
Gene start: 166733384
Gene end: 167234796
  
Corresponding Affymetrix probe sets: 1554418_s_at (Human Genome U133 Plus 2.0 Array)   206433_s_at (Human Genome U133 Plus 2.0 Array)   206434_at (Human Genome U133 Plus 2.0 Array)   235342_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425407
Ensembl peptide - ENSP00000444789
Ensembl peptide - ENSP00000441396
Ensembl peptide - ENSP00000426995
Ensembl peptide - ENSP00000426716
Ensembl peptide - ENSP00000426318
Ensembl peptide - ENSP00000426177
Ensembl peptide - ENSP00000425859
Ensembl peptide - ENSP00000425712
Ensembl peptide - ENSP00000425570
Ensembl peptide - ENSP00000425502
Ensembl peptide - ENSP00000349677
Ensembl peptide - ENSP00000350153
Ensembl peptide - ENSP00000411344
Ensembl peptide - ENSP00000420920
Ensembl peptide - ENSP00000420928
Ensembl peptide - ENSP00000422170
Ensembl peptide - ENSP00000422336
Ensembl peptide - ENSP00000423176
Ensembl peptide - ENSP00000423367
Ensembl peptide - ENSP00000423421
Ensembl peptide - ENSP00000423606
Ensembl peptide - ENSP00000424168
Ensembl peptide - ENSP00000424674
Ensembl peptide - ENSP00000424677
Ensembl peptide - ENSP00000424980
NCBI entrez gene - 50859     See in Manteia.
OMIM - 607989
RefSeq - XM_017008258
RefSeq - NM_001040159
RefSeq - NM_001204352
RefSeq - NM_001204353
RefSeq - NM_001204354
RefSeq - NM_001204355
RefSeq - NM_001204356
RefSeq - NM_001204358
RefSeq - NM_001251967
RefSeq - NM_016950
RefSeq - XM_011532018
RefSeq - XM_017008257
RefSeq Peptide - NP_001191285
RefSeq Peptide - NP_001191287
RefSeq Peptide - NP_001238896
RefSeq Peptide - NP_058646
RefSeq Peptide - NP_001035249
RefSeq Peptide - NP_001191281
RefSeq Peptide - NP_001191282
RefSeq Peptide - NP_001191283
RefSeq Peptide - NP_001191284
swissprot - H0YA19
swissprot - E7EQ24
swissprot - E7ENY3
swissprot - E7ENT7
swissprot - E7ENM6
swissprot - E7EMP8
swissprot - B4DG04
swissprot - Q4W5S3
swissprot - Q9BQ16
swissprot - E7EVH4
swissprot - A0A0A0MTJ2
swissprot - E7ESN1
Ensembl - ENSG00000196104
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spock3ENSDARG00000070266Danio rerio
 SPOCK3ENSGALG00000009568Gallus gallus
 Q8BKV0ENSMUSG00000054162Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q08629 / SPOCK1 / SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1ENSG0000015237751
Q92563 / SPOCK2 / SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2ENSG0000010774245


Protein motifs (from Interpro)
Interpro ID Name
 IPR000716  Thyroglobulin type-1
 IPR002350  Kazal domain
 IPR011992  EF-hand domain pair
 IPR019577  SPARC/Testican, calcium-binding domain
 IPR036058  Kazal domain superfamily
 IPR036857  Thyroglobulin type-1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity TAS
 biological_processGO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan IEA
 biological_processGO:2000146 negative regulation of cell motility TAS
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004857 enzyme inhibitor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding IEA
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity TAS
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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