ENSG00000196313


Homo sapiens

Features
Gene ID: ENSG00000196313
  
Biological name :POM121
  
Synonyms : POM121 / POM121 transmembrane nucleoporin / Q96HA1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q11.23
Gene start: 72879365
Gene end: 72951440
  
Corresponding Affymetrix probe sets: 205096_at (Human Genome U133 Plus 2.0 Array)   212178_s_at (Human Genome U133 Plus 2.0 Array)   213360_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378687
Ensembl peptide - ENSP00000351124
Ensembl peptide - ENSP00000405562
Ensembl peptide - ENSP00000486504
Ensembl peptide - ENSP00000393020
NCBI entrez gene - 9883     See in Manteia.
OMIM - 615753
RefSeq - XM_017012854
RefSeq - NM_001257190
RefSeq - NM_172020
RefSeq - XM_006716196
RefSeq - XM_011516730
RefSeq - XM_017012853
RefSeq - XM_005250726
RefSeq - XM_005250727
RefSeq Peptide - NP_742017
RefSeq Peptide - NP_001244119
swissprot - Q96HA1
Ensembl - ENSG00000196313
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pom121ENSDARG00000055113Danio rerio
 ENSGALG00000029674Gallus gallus
 Pom121ENSMUSG00000053293Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
POM121C / POM121 transmembrane nucleoporin CENSG0000027239194
Q96KW2 / POM121L2 / POM121 transmembrane nucleoporin like 2ENSG0000015855338
Q8N7R1 / POM121L12 / POM121 transmembrane nucleoporin like 12ENSG000002219005


Protein motifs (from Interpro)
Interpro ID Name
 IPR026054  Nuclear pore complex protein
 IPR026090  Nuclear pore protein POM121


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006405 RNA export from nucleus IBA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0043657 host cell IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0017056 structural constituent of nuclear pore IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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