ENSG00000197448


Homo sapiens

Features
Gene ID: ENSG00000197448
  
Biological name :GSTK1
  
Synonyms : glutathione S-transferase kappa 1 / GSTK1 / Q9Y2Q3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q34
Gene start: 143244093
Gene end: 143270854
  
Corresponding Affymetrix probe sets: 217751_at (Human Genome U133 Plus 2.0 Array)   239333_x_at (Human Genome U133 Plus 2.0 Array)   243325_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408341
Ensembl peptide - ENSP00000406802
Ensembl peptide - ENSP00000415813
Ensembl peptide - ENSP00000431049
Ensembl peptide - ENSP00000351181
Ensembl peptide - ENSP00000386944
NCBI entrez gene - 373156     See in Manteia.
OMIM - 602321
RefSeq - NM_001143679
RefSeq - NM_001143680
RefSeq - NM_001143681
RefSeq - NM_015917
RefSeq Peptide - NP_057001
RefSeq Peptide - NP_001137151
RefSeq Peptide - NP_001137152
RefSeq Peptide - NP_001137153
swissprot - Q6FII1
swissprot - Q9Y2Q3
swissprot - E9PFN5
swissprot - C9JNT3
Ensembl - ENSG00000197448
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR854927.4ENSDARG00000110055Danio rerio
 gstk1ENSDARG00000056510Danio rerio
 gstk2ENSDARG00000019585Danio rerio
 gstk4ENSDARG00000092052Danio rerio
 gstk4ENSDARG00000093119Danio rerio
 GSTK1ENSGALG00000014708Gallus gallus
 Gstk1ENSMUSG00000029864Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001853  DSBA-like thioredoxin domain
 IPR014440  HCCA isomerase/glutathione S-transferase kappa
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0030855 epithelial cell differentiation IEP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004364 glutathione transferase activity TAS
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000197448 GSTK1 / Q9Y2Q3 / glutathione S-transferase kappa 1  / complex






 

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