ENSG00000198081


Homo sapiens

Features
Gene ID: ENSG00000198081
  
Biological name :ZBTB14
  
Synonyms : O43829 / ZBTB14 / zinc finger and BTB domain containing 14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: p11.31
Gene start: 5289019
Gene end: 5297053
  
Corresponding Affymetrix probe sets: 208199_s_at (Human Genome U133 Plus 2.0 Array)   209724_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484129
Ensembl peptide - ENSP00000349503
Ensembl peptide - ENSP00000383009
Ensembl peptide - ENSP00000463555
Ensembl peptide - ENSP00000478971
Ensembl peptide - ENSP00000462112
Ensembl peptide - ENSP00000463414
NCBI entrez gene - 7541     See in Manteia.
OMIM - 602126
RefSeq - NM_001143823
RefSeq - NM_001243704
RefSeq - NM_003409
RefSeq - NM_001243702
RefSeq Peptide - NP_001137295
RefSeq Peptide - NP_001230633
RefSeq Peptide - NP_003400
RefSeq Peptide - NP_001230631
swissprot - O43829
swissprot - J3KRQ2
swissprot - J3QL74
swissprot - J3QLI2
Ensembl - ENSG00000198081
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb14ENSDARG00000098273Danio rerio
 ZBTB14ENSGALG00000038340Gallus gallus
 Q08376ENSMUSG00000049672Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NAP3 / ZBTB38 / zinc finger and BTB domain containing 38ENSG0000017731127
Q9ULJ3 / ZBTB21 / zinc finger and BTB domain containing 21ENSG0000017327624
Q86T24 / ZBTB33 / zinc finger and BTB domain containing 33ENSG0000017748522
ZBTB4 / Q9P1Z0 / zinc finger and BTB domain containing 4ENSG0000017428219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0003170 heart valve development IEA
 biological_processGO:0003279 cardiac septum development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0060976 coronary vasculature development IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016235 aggresome IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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