ENSG00000174282


Homo sapiens

Features
Gene ID: ENSG00000174282
  
Biological name :ZBTB4
  
Synonyms : Q9P1Z0 / ZBTB4 / zinc finger and BTB domain containing 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7459366
Gene end: 7484263
  
Corresponding Affymetrix probe sets: 225629_s_at (Human Genome U133 Plus 2.0 Array)   227047_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307858
Ensembl peptide - ENSP00000369973
NCBI entrez gene - 57659     See in Manteia.
OMIM - 612308
RefSeq - XM_011523972
RefSeq - NM_001128833
RefSeq - NM_020899
RefSeq - XM_006721563
RefSeq - XM_006721564
RefSeq Peptide - NP_001122305
RefSeq Peptide - NP_065950
swissprot - Q9P1Z0
Ensembl - ENSG00000174282
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb4ENSDARG00000105255Danio rerio
 Zbtb4ENSMUSG00000018750Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NAP3 / ZBTB38 / zinc finger and BTB domain containing 38ENSG0000017731128
Q86T24 / ZBTB33 / zinc finger and BTB domain containing 33ENSG0000017748513
Q9ULJ3 / ZBTB21 / zinc finger and BTB domain containing 21ENSG0000017327612
O43829 / ZBTB14 / zinc finger and BTB domain containing 14ENSG000001980819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008327 methyl-CpG binding IDA
 molecular_functionGO:0010428 methyl-CpNpG binding IDA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr