ENSMUSG00000018750


Mus musculus

Features
Gene ID: ENSMUSG00000018750
  
Biological name :Zbtb4
  
Synonyms : Q5F293 / Zbtb4 / zinc finger and BTB domain containing 4
  
Possible biological names infered from orthology : Q9P1Z0
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 69765912
Gene end: 69784023
  
Corresponding Affymetrix probe sets: 10377593 (MoGene1.0st)   1429722_at (Mouse Genome 430 2.0 Array)   1453266_at (Mouse Genome 430 2.0 Array)   1457293_at (Mouse Genome 430 2.0 Array)   1460488_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118027
Ensembl peptide - ENSMUSP00000115687
Ensembl peptide - ENSMUSP00000121694
Ensembl peptide - ENSMUSP00000104278
Ensembl peptide - ENSMUSP00000104279
Ensembl peptide - ENSMUSP00000104280
Ensembl peptide - ENSMUSP00000104282
NCBI entrez gene - 75580     See in Manteia.
MGI - MGI:1922830
RefSeq - XM_011249293
RefSeq - NM_029348
RefSeq - XM_006534389
RefSeq - XM_006534390
RefSeq - XM_006534391
RefSeq - XM_006534392
RefSeq - XM_006534393
RefSeq - XM_006534394
RefSeq Peptide - NP_083624
swissprot - B0QZJ2
swissprot - B0QZJ3
swissprot - Q5F293
swissprot - Q5F295
swissprot - Q5F296
swissprot - Q14DI5
Ensembl - ENSMUSG00000018750
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb4ENSDARG00000105255Danio rerio
 ZBTB4ENSG00000174282Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zbtb38 / zinc finger and BTB domain containing 38 / Q8NAP3*ENSMUSG0000004043328
Q8BN78 / Zbtb33 / zinc finger and BTB domain containing 33 / Q86T24*ENSMUSG0000004804714
Zbtb21 / zinc finger and BTB domain containing 21 / Q9ULJ3*ENSMUSG0000004696213
Q08376 / Zbtb14 / zinc finger and BTB domain containing 14 / O43829*ENSMUSG000000496729


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008327 methyl-CpG binding IEA
 molecular_functionGO:0010428 methyl-CpNpG binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001289 persistence of hyaloid capillary system "failure of the degeneration of the transient vascular system of the eye during development" [J:49840]
Show

Allelic Composition: Srd5a3tm1b(EUCOMM)Wtsi/Srd5a3tm1b(EUCOMM)Wtsi
Genetic Background: B6N(Cg)-Srd5a3tm1b(EUCOMM)Wtsi/J

 MP:0001307 fused cornea/lens "condition in which the transparent anterior portion of the fibrous coat of the eye is joined to the transparent biconvex cellular refractive structure lying between the iris and vitreous humor of the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Srd5a3tm1b(EUCOMM)Wtsi/Srd5a3tm1b(EUCOMM)Wtsi
Genetic Background: B6N(Cg)-Srd5a3tm1b(EUCOMM)Wtsi/J

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Srd5a3tm1b(EUCOMM)Wtsi/Srd5a3tm1b(EUCOMM)Wtsi
Genetic Background: B6N(Cg)-Srd5a3tm1b(EUCOMM)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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