ENSMUSG00000048047


Mus musculus

Features
Gene ID: ENSMUSG00000048047
  
Biological name :Zbtb33
  
Synonyms : Q8BN78 / Zbtb33 / zinc finger and BTB domain containing 33
  
Possible biological names infered from orthology : Q86T24
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A3.3
Gene start: 38189793
Gene end: 38197046
  
Corresponding Affymetrix probe sets: 10599321 (MoGene1.0st)   1421094_at (Mouse Genome 430 2.0 Array)   1434022_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110795
Ensembl peptide - ENSMUSP00000118993
Ensembl peptide - ENSMUSP00000049983
NCBI entrez gene - 56805     See in Manteia.
MGI - MGI:1927290
RefSeq - NM_020256
RefSeq - NM_001079513
RefSeq Peptide - NP_001072981
RefSeq Peptide - NP_064652
swissprot - Q8BN78
swissprot - A2A3Z3
swissprot - A2A3Z2
Ensembl - ENSMUSG00000048047
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb33ENSDARG00000071467Danio rerio
 ZBTB33ENSGALG00000008611Gallus gallus
 Q86T24ENSG00000177485Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zbtb38 / zinc finger and BTB domain containing 38 / Q8NAP3*ENSMUSG0000004043326
Zbtb4 / Q5F293 / zinc finger and BTB domain containing 4 / Q9P1Z0*ENSMUSG0000001875020
Zbtb21 / zinc finger and BTB domain containing 21 / Q9ULJ3*ENSMUSG0000004696215
Q08376 / Zbtb14 / zinc finger and BTB domain containing 14 / O43829*ENSMUSG0000004967214


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated ISA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008327 methyl-CpG binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Zbtb33tm1.1Bird/Zbtb33tm1.1Bird
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Faslpr/Faslpr
Genetic Background: MRL/Mp-Faslpr atms

Allelic Composition: Zbtb33tm1.1Bird/Zbtb33tm1.1Bird
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002404 intestinal adenoma "benign tumors of the small and large intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: ApcMin/Apc+,Zbtb33tm1.1Bird/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J

 MP:0003447 reduced tumor growth/size "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383]
Show

Allelic Composition: ApcMin/Apc+,Zbtb33tm1.1Bird/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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