ENSG00000198178


Homo sapiens

Features
Gene ID: ENSG00000198178
  
Biological name :CLEC4C
  
Synonyms : CLEC4C / C-type lectin domain family 4 member C / Q8WTT0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.31
Gene start: 7729415
Gene end: 7751605
  
Corresponding Affymetrix probe sets: 1552552_s_at (Human Genome U133 Plus 2.0 Array)   1555687_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445338
Ensembl peptide - ENSP00000440428
Ensembl peptide - ENSP00000442457
Ensembl peptide - ENSP00000346648
Ensembl peptide - ENSP00000353500
Ensembl peptide - ENSP00000438649
NCBI entrez gene - 170482     See in Manteia.
OMIM - 606677
RefSeq - XM_017018940
RefSeq - NM_130441
RefSeq - NM_203503
RefSeq Peptide - NP_569708
RefSeq Peptide - NP_987099
swissprot - H0YFH6
swissprot - H0YGB2
swissprot - Q8WTT0
Ensembl - ENSG00000198178
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 illr1ENSDARG00000059254Danio rerio
 illr2ENSDARG00000094882Danio rerio
 illr3ENSDARG00000018327Danio rerio
 illr4ENSDARG00000008075Danio rerio
 si:ch211-133n4.11ENSDARG00000094796Danio rerio
 si:ch211-133n4.12ENSDARG00000092749Danio rerio
 si:ch211-133n4.7ENSDARG00000095424Danio rerio
 si:ch211-232p21.6ENSDARG00000089377Danio rerio
 si:ch73-86n18.1ENSDARG00000056379Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLEC6A / Q6EIG7 / C-type lectin domain containing 6AENSG0000020584650
CLEC4A / Q9UMR7 / C-type lectin domain family 4 member AENSG0000011172946
CLEC4D / Q8WXI8 / C-type lectin domain family 4 member DENSG0000016652740


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033989  CD209-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Dectin-2 family
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000158869 FCER1G / P30273 / Fc fragment of IgE receptor Ig  / complex






 

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