ENSG00000198242


Homo sapiens

Features
Gene ID: ENSG00000198242
  
Biological name :RPL23A
  
Synonyms : P62750 / ribosomal protein L23a / RPL23A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q11.2
Gene start: 28719393
Gene end: 28724359
  
Corresponding Affymetrix probe sets: 203012_x_at (Human Genome U133 Plus 2.0 Array)   208825_x_at (Human Genome U133 Plus 2.0 Array)   208834_x_at (Human Genome U133 Plus 2.0 Array)   213084_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466425
Ensembl peptide - ENSP00000468172
Ensembl peptide - ENSP00000468402
Ensembl peptide - ENSP00000347969
Ensembl peptide - ENSP00000378396
Ensembl peptide - ENSP00000389103
Ensembl peptide - ENSP00000465342
NCBI entrez gene - 6147     See in Manteia.
OMIM - 602326
RefSeq - NM_000984
RefSeq Peptide - NP_000975
swissprot - K7EJV9
swissprot - K7EMA7
swissprot - K7ERT8
swissprot - A8MUS3
swissprot - P62750
swissprot - H7BY10
Ensembl - ENSG00000198242
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl23aENSDARG00000006316Danio rerio
 RPL23AENSGALG00000003966Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001014  Ribosomal protein L23/L25, conserved site
 IPR005633  Ribosomal protein L23/L25, N-terminal
 IPR012678  Ribosomal protein L23/L15e core domain superfamily
 IPR013025  Ribosomal protein L25/L23
 IPR019985  Ribosomal protein L23


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IBA
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0019083 viral transcription TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus HDA
 cellular_componentGO:0005737 cytoplasm HDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit NAS
 cellular_componentGO:0031932 TORC2 complex ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019843 rRNA binding IEA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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