ENSG00000198563


Homo sapiens

Features
Gene ID: ENSG00000198563
  
Biological name :DDX39B
  
Synonyms : DDX39B / DExD-box helicase 39B / Q13838
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.33
Gene start: 31530219
Gene end: 31542448
  
Corresponding Affymetrix probe sets: 200041_s_at (Human Genome U133 Plus 2.0 Array)   212384_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410313
Ensembl peptide - ENSP00000416269
Ensembl peptide - ENSP00000436220
Ensembl peptide - ENSP00000416350
Ensembl peptide - ENSP00000365347
Ensembl peptide - ENSP00000379475
Ensembl peptide - ENSP00000392672
Ensembl peptide - ENSP00000393984
Ensembl peptide - ENSP00000399371
Ensembl peptide - ENSP00000399841
Ensembl peptide - ENSP00000405245
Ensembl peptide - ENSP00000405707
Ensembl peptide - ENSP00000406422
Ensembl peptide - ENSP00000408000
Ensembl peptide - ENSP00000409426
NCBI entrez gene - 7919     See in Manteia.
OMIM - 142560
RefSeq - NM_004640
RefSeq - NM_080598
RefSeq Peptide - NP_004631
RefSeq Peptide - NP_542165
swissprot - F6S2B7
swissprot - F6S4E6
swissprot - F6SXL5
swissprot - F6TRA5
swissprot - F6U6E2
swissprot - F6UJC5
swissprot - F6WLT2
swissprot - H0Y400
swissprot - H0YCC6
swissprot - Q13838
swissprot - A0A0A0MT12
swissprot - Q5STU3
swissprot - A0A024RCM3
swissprot - F6QYI9
swissprot - F6R6M7
Ensembl - ENSG00000198563
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ddx39bENSMUSG00000019432Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX39A / O00148 / DExD-box helicase 39AENSG0000012313689
DDX20 / Q9UHI6 / DEAD-box helicase 20ENSG0000006470332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000245 spliceosomal complex assembly IDA
 biological_processGO:0000398 mRNA splicing, via spliceosome IGI
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus IGI
 biological_processGO:0008380 RNA splicing IDA
 biological_processGO:0010501 RNA secondary structure unwinding IDA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation IMP
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0046784 viral mRNA export from host cell nucleus IDA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0061051 positive regulation of cell growth involved in cardiac muscle cell development IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:2000002 negative regulation of DNA damage checkpoint IMP
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IEA
 cellular_componentGO:0000346 transcription export complex IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IDA
 cellular_componentGO:0005687 U4 snRNP IDA
 cellular_componentGO:0005688 U6 snRNP IDA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity TAS
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008186 RNA-dependent ATPase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity EXP
 molecular_functionGO:0017070 U6 snRNA binding IDA
 molecular_functionGO:0030621 U4 snRNA binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043008 ATP-dependent protein binding IDA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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