ENSG00000064703


Homo sapiens

Features
Gene ID: ENSG00000064703
  
Biological name :DDX20
  
Synonyms : DDX20 / DEAD-box helicase 20 / Q9UHI6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.2
Gene start: 111755245
Gene end: 111768016
  
Corresponding Affymetrix probe sets: 223331_s_at (Human Genome U133 Plus 2.0 Array)   224315_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358716
Ensembl peptide - ENSP00000435660
Ensembl peptide - ENSP00000434085
NCBI entrez gene - 11218     See in Manteia.
OMIM - 606168
RefSeq - NM_007204
RefSeq Peptide - NP_009135
swissprot - E9PJ60
swissprot - Q9UHI6
Ensembl - ENSG00000064703
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx20ENSDARG00000061204Danio rerio
 DDX20ENSGALG00000001504Gallus gallus
 Ddx20ENSMUSG00000027905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX39A / O00148 / DExD-box helicase 39AENSG0000012313617
DDX39B / Q13838 / DExD-box helicase 39BENSG0000019856317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000244 spliceosomal tri-snRNP complex assembly TAS
 biological_processGO:0000387 spliceosomal snRNP assembly TAS
 biological_processGO:0006396 RNA processing TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048477 oogenesis IEA
 biological_processGO:0050810 regulation of steroid biosynthetic process IEA
 biological_processGO:0051170 import into nucleus TAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 cellular_componentGO:0032797 SMN complex IDA
 cellular_componentGO:0034719 SMN-Sm protein complex IDA
 cellular_componentGO:0090571 RNA polymerase II transcription repressor complex IEA
 cellular_componentGO:0097504 Gemini of coiled bodies IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity TAS
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0070491 repressing transcription factor binding IPI


Pathways (from Reactome)
Pathway description
snRNP Assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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