ENSG00000123136


Homo sapiens

Features
Gene ID: ENSG00000123136
  
Biological name :DDX39A
  
Synonyms : DDX39A / DExD-box helicase 39A / O00148
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.12
Gene start: 14408819
Gene end: 14419383
  
Corresponding Affymetrix probe sets: 201584_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467911
Ensembl peptide - ENSP00000485838
Ensembl peptide - ENSP00000242776
Ensembl peptide - ENSP00000322749
Ensembl peptide - ENSP00000392929
Ensembl peptide - ENSP00000464801
Ensembl peptide - ENSP00000465926
Ensembl peptide - ENSP00000466810
Ensembl peptide - ENSP00000467040
Ensembl peptide - ENSP00000467411
Ensembl peptide - ENSP00000467862
NCBI entrez gene - 10212     See in Manteia.
RefSeq - NM_005804
RefSeq - XM_006722606
RefSeq - XM_011527620
RefSeq - XM_011527621
RefSeq Peptide - NP_005795
swissprot - K7EPJ3
swissprot - A0A0D9SEM9
swissprot - O00148
swissprot - K7EQN7
swissprot - K7EIL8
swissprot - K7EL56
swissprot - K7EN69
swissprot - K7ENP6
Ensembl - ENSG00000123136
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx39aaENSDARG00000006225Danio rerio
 ddx39abENSDARG00000015111Danio rerio
 Ddx39ENSMUSG00000005481Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX39B / Q13838 / DExD-box helicase 39BENSG0000019856390
DDX20 / Q9UHI6 / DEAD-box helicase 20ENSG0000006470332


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IGI
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus IGI
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity EXP
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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