ENSMUSG00000005481


Mus musculus

Features
Gene ID: ENSMUSG00000005481
  
Biological name :Ddx39
  
Synonyms : ATP-dependent RNA helicase DDX39A / Ddx39 / Q8VDW0
  
Possible biological names infered from orthology : DDX39A / DExD-box helicase 39A / O00148
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C2
Gene start: 83715177
Gene end: 83726892
  
Corresponding Affymetrix probe sets: 10573217 (MoGene1.0st)   1423643_at (Mouse Genome 430 2.0 Array)   1438168_x_at (Mouse Genome 430 2.0 Array)   1438287_x_at (Mouse Genome 430 2.0 Array)   1451065_a_at (Mouse Genome 430 2.0 Array)   1455814_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105435
Ensembl peptide - ENSMUSP00000132222
Ensembl peptide - ENSMUSP00000148329
Ensembl peptide - ENSMUSP00000019576
Ensembl peptide - ENSMUSP00000116101
NCBI entrez gene - 68278     See in Manteia.
MGI - MGI:1915528
RefSeq - XM_017312952
RefSeq - NM_197982
RefSeq - XM_017312949
RefSeq - XM_017312950
RefSeq - XM_017312951
RefSeq - XM_006531332
RefSeq Peptide - NP_932099
swissprot - Q8VDW0
swissprot - D6RHT5
Ensembl - ENSMUSG00000005481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx39aaENSDARG00000006225Danio rerio
 ddx39abENSDARG00000015111Danio rerio
 DDX39AENSG00000123136Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ddx39b / Q9Z1N5 / Spliceosome RNA helicase Ddx39b / Q13838* / DExD-box helicase 39B*ENSMUSG0000001943291
Ddx20 / Q9JJY4 / Probable ATP-dependent RNA helicase DDX20 / Q9UHI6* / DEAD-box helicase 20*ENSMUSG0000002790533


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006406 mRNA export from nucleus IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005681 spliceosomal complex IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity ISO
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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