ENSG00000198586


Homo sapiens

Features
Gene ID: ENSG00000198586
  
Biological name :TLK1
  
Synonyms : Q9UKI8 / TLK1 / tousled like kinase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q31.1
Gene start: 170990823
Gene end: 171231314
  
Corresponding Affymetrix probe sets: 202606_s_at (Human Genome U133 Plus 2.0 Array)   210379_s_at (Human Genome U133 Plus 2.0 Array)   211077_s_at (Human Genome U133 Plus 2.0 Array)   222966_at (Human Genome U133 Plus 2.0 Array)   241642_x_at (Human Genome U133 Plus 2.0 Array)   241643_at (Human Genome U133 Plus 2.0 Array)   244389_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000409222
Ensembl peptide - ENSP00000393165
Ensembl peptide - ENSP00000411099
Ensembl peptide - ENSP00000428113
Ensembl peptide - ENSP00000352810
Ensembl peptide - ENSP00000354089
Ensembl peptide - ENSP00000387313
NCBI entrez gene - 9874     See in Manteia.
OMIM - 608438
RefSeq - XM_017005422
RefSeq - NM_001136554
RefSeq - NM_001136555
RefSeq - NM_012290
RefSeq - XM_011512238
RefSeq - XM_017005421
RefSeq Peptide - NP_036422
RefSeq Peptide - NP_001130027
RefSeq Peptide - NP_001130026
swissprot - B3KRP1
swissprot - F8W7X8
swissprot - C9JWT6
swissprot - Q9UKI8
Ensembl - ENSG00000198586
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tlk1aENSDARG00000042467Danio rerio
 tlk1bENSDARG00000100715Danio rerio
 TLK1ENSGALG00000009569Gallus gallus
 Tlk1ENSMUSG00000041997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLK2 / Q86UE8 / tousled like kinase 2ENSG0000014687270
TTK / P33981 / TTK protein kinaseENSG0000011274217


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001672 regulation of chromatin assembly or disassembly IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006886 intracellular protein transport IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IDA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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