ENSG00000198730


Homo sapiens

Features
Gene ID: ENSG00000198730
  
Biological name :CTR9
  
Synonyms : CTR9 / CTR9 homolog, Paf1/RNA polymerase II complex component / Q6PD62
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.4
Gene start: 10750987
Gene end: 10801625
  
Corresponding Affymetrix probe sets: 200833_s_at (Human Genome U133 Plus 2.0 Array)   202060_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000493551
Ensembl peptide - ENSP00000355013
Ensembl peptide - ENSP00000431458
NCBI entrez gene - 9646     See in Manteia.
OMIM - 609366
RefSeq - NM_014633
RefSeq Peptide - NP_055448
swissprot - H0YCE8
swissprot - Q6PD62
Ensembl - ENSG00000198730
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctr9ENSDARG00000009170Danio rerio
 CTR9ENSGALG00000005618Gallus gallus
 Ctr9ENSMUSG00000005609Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR027363  Methylthioribose-1-phosphate isomerase, N-terminal
 IPR031101  RNA polymerase-associated protein Ctr9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001711 endodermal cell fate commitment IEA
 biological_processGO:0001826 inner cell mass cell differentiation IEA
 biological_processGO:0001829 trophectodermal cell differentiation IEA
 biological_processGO:0001832 blastocyst growth IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0007259 JAK-STAT cascade IEA
 biological_processGO:0010390 histone monoubiquitination IDA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0016570 histone modification IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IDA
 biological_processGO:0033523 histone H2B ubiquitination IDA
 biological_processGO:0045638 negative regulation of myeloid cell differentiation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0051571 positive regulation of histone H3-K4 methylation IEA
 biological_processGO:0070102 interleukin-6-mediated signaling pathway IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0080182 histone H3-K4 trimethylation IEA
 biological_processGO:1900364 negative regulation of mRNA polyadenylation IMP
 biological_processGO:2000653 regulation of genetic imprinting IEA
 biological_processGO:2001162 positive regulation of histone H3-K79 methylation IMP
 biological_processGO:2001168 positive regulation of histone H2B ubiquitination IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016593 Cdc73/Paf1 complex IDA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0035327 transcriptionally active chromatin IEA
 molecular_functionGO:0000993 RNA polymerase II core binding IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042169 SH2 domain binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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