ENSG00000198758


Homo sapiens

Features
Gene ID: ENSG00000198758
  
Biological name :EPS8L3
  
Synonyms : EPS8L3 / EPS8 like 3 / Q8TE67
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.3
Gene start: 109750080
Gene end: 109764027
  
Corresponding Affymetrix probe sets: 219404_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000483789
Ensembl peptide - ENSP00000354551
Ensembl peptide - ENSP00000355255
Ensembl peptide - ENSP00000358820
NCBI entrez gene - 79574     See in Manteia.
OMIM - 614989
RefSeq - XM_017002329
RefSeq - NM_001319952
RefSeq - NM_024526
RefSeq - NM_133181
RefSeq - NM_139053
RefSeq - XM_011542132
RefSeq - XM_011542133
RefSeq - XM_011542134
RefSeq - XM_011542135
RefSeq - XM_017002327
RefSeq - XM_017002328
RefSeq Peptide - NP_001306881
RefSeq Peptide - NP_078802
RefSeq Peptide - NP_573444
RefSeq Peptide - NP_620641
swissprot - Q8TE67
swissprot - A0A087X104
Ensembl - ENSG00000198758
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eps8l3aENSDARG00000101979Danio rerio
 eps8l3bENSDARG00000005704Danio rerio
 Eps8l3ENSMUSG00000040600Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPS8 / Q12929 / epidermal growth factor receptor pathway substrate 8ENSG0000015149132
EPS8L1 / Q8TE68 / EPS8 like 1ENSG0000013103731
EPS8L2 / Q9H6S3 / EPS8 like 2ENSG0000017710630


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR011993  PH-like domain superfamily
 IPR013625  Tensin/EPS8 phosphotyrosine-binding domain
 IPR033928  Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain
 IPR035462  Eps8, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042634 regulation of hair cycle IMP
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0001596 Alopecia "Loss of hair from the head or body." [HPO:curators]
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 HP:0002208 Coarse hair 
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 HP:0002209 Sparse scalp hair "Sparseness of the `head hair` (FMA:54241)." [HPO:probinson]
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 HP:0100840 Aplasia/Hypoplasia of the eyebrow "Absence or underdevelopment of the eyebrow." [HPO:probinson]
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 HP:0200102 Sparse/absent eyelashes 
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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