ENSMUSG00000040600


Mus musculus

Features
Gene ID: ENSMUSG00000040600
  
Biological name :Eps8l3
  
Synonyms : Epidermal growth factor receptor kinase substrate 8-like protein 3 / Eps8l3 / Q91WL0
  
Possible biological names infered from orthology : EPS8 like 3 / Q8TE67
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.3
Gene start: 107877229
Gene end: 107892900
  
Corresponding Affymetrix probe sets: 10495223 (MoGene1.0st)   1448798_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042004
Ensembl peptide - ENSMUSP00000143754
NCBI entrez gene - 99662     See in Manteia.
MGI - MGI:2139743
RefSeq - XM_006502465
RefSeq - NM_133867
RefSeq - XM_006502463
RefSeq - XM_006502464
RefSeq Peptide - NP_598628
swissprot - A0A0G2JGZ0
swissprot - Q91WL0
Ensembl - ENSMUSG00000040600
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eps8l3aENSDARG00000101979Danio rerio
 eps8l3bENSDARG00000005704Danio rerio
 EPS8L3ENSG00000198758Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eps8 / Q08509 / Epidermal growth factor receptor kinase substrate 8 / Q12929* / epidermal growth factor receptor pathway substrate 8*ENSMUSG0000001576630
Eps8l1 / Q8R5F8 / Epidermal growth factor receptor kinase substrate 8-like protein 1 / Q8TE68* / EPS8 like 1*ENSMUSG0000000615429
Eps8l2 / Q99K30 / Epidermal growth factor receptor kinase substrate 8-like protein 2 / Q9H6S3* / EPS8 like 2*ENSMUSG0000002550429


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR011993  PH-like domain superfamily
 IPR013625  Tensin/EPS8 phosphotyrosine-binding domain
 IPR033928  Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain
 IPR035462  Eps8, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042634 regulation of hair cycle IEA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0000455 abnormal maxilla morphology "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0005635 decreased circulating bilirubin level "less thant the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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