ENSG00000198924


Homo sapiens

Features
Gene ID: ENSG00000198924
  
Biological name :DCLRE1A
  
Synonyms : DCLRE1A / DNA cross-link repair 1A / Q6PJP8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q25.3
Gene start: 113834725
Gene end: 113854383
  
Corresponding Affymetrix probe sets: 209804_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355185
Ensembl peptide - ENSP00000358311
NCBI entrez gene - 9937     See in Manteia.
OMIM - 609682
RefSeq - XM_011540429
RefSeq - NM_001271816
RefSeq - NM_014881
RefSeq - XM_006718090
RefSeq Peptide - NP_001258745
RefSeq Peptide - NP_055696
swissprot - Q6PJP8
Ensembl - ENSG00000198924
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dclre1aENSDARG00000091768Danio rerio
 DCLRE1AENSGALG00000008938Gallus gallus
 Dclre1aENSMUSG00000025077Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96SD1 / DCLRE1C / DNA cross-link repair 1CENSG000001524578
Q9H816 / DCLRE1B / DNA cross-link repair 1BENSG000001186555


Protein motifs (from Interpro)
Interpro ID Name
 IPR011084  DNA repair metallo-beta-lactamase
 IPR036866  Ribonuclease Z/Hydroxyacylglutathione hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0031848 protection from non-homologous end joining at telomere IBA
 biological_processGO:0036297 interstrand cross-link repair TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IBA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0035312 5"-3" exodeoxyribonuclease activity IDA


Pathways (from Reactome)
Pathway description
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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