ENSG00000205755


Homo sapiens

Features
Gene ID: ENSG00000205755
  
Biological name :CRLF2
  
Synonyms : CRLF2 / cytokine receptor like factor 2 / Q9HC73
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.33
Gene start: 1187549
Gene end: 1212750
  
Corresponding Affymetrix probe sets: 208303_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370978
Ensembl peptide - ENSP00000370979
Ensembl peptide - ENSP00000485269
Ensembl peptide - ENSP00000383641
NCBI entrez gene - 64109     See in Manteia.
OMIM - 300357
OMIM - 400023
RefSeq - XM_011546181
RefSeq - XM_011545634
RefSeq - NM_001012288
RefSeq - NM_022148
RefSeq - XM_011546182
RefSeq Peptide - NP_071431
RefSeq Peptide - NP_001012288
swissprot - Q9HC73
swissprot - D0E2W4
swissprot - A0A0C4DH06
Ensembl - ENSG00000205755
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CRLF2ENSGALG00000045814Gallus gallus
 Crlf2ENSMUSG00000033467Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway IDA
 biological_processGO:0033005 positive regulation of mast cell activation IMP
 biological_processGO:0038111 interleukin-7-mediated signaling pathway TAS
 biological_processGO:1904894 positive regulation of STAT cascade IDA
 biological_processGO:2000664 positive regulation of interleukin-5 secretion IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IMP
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-7 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex
 ENSG00000168685 IL7R / P16871 / interleukin 7 receptor  / complex
 ENSG00000145777 TSLP / Q969D9 / thymic stromal lymphopoietin  / complex






 

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