ENSG00000213676


Homo sapiens

Features
Gene ID: ENSG00000213676
  
Biological name :ATF6B
  
Synonyms : activating transcription factor 6 beta / ATF6B / Q99941
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.32
Gene start: 32115264
Gene end: 32128253
  
Corresponding Affymetrix probe sets: 1554487_a_at (Human Genome U133 Plus 2.0 Array)   203168_at (Human Genome U133 Plus 2.0 Array)   211611_s_at (Human Genome U133 Plus 2.0 Array)   216208_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393419
Ensembl peptide - ENSP00000364347
Ensembl peptide - ENSP00000364349
NCBI entrez gene - 1388     See in Manteia.
OMIM - 600984
RefSeq - NM_004381
RefSeq - NM_001136153
RefSeq Peptide - NP_001129625
RefSeq Peptide - NP_004372
swissprot - Q99941
swissprot - A0A1U9X796
swissprot - H0Y7D7
Ensembl - ENSG00000213676
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Atf6bENSMUSG00000015461Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATF6 / P18850 / activating transcription factor 6ENSG0000011821732


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR029809  cAMP-dependent transcription factor ATF-6 beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated TAS
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0036500 ATF6-mediated unfolded protein response TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:1903892 negative regulation of ATF6-mediated unfolded protein response IDA
 biological_processGO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IDA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane TAS
 cellular_componentGO:0032993 protein-DNA complex IDA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035497 cAMP response element binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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