ENSG00000215475


Homo sapiens

Features
Gene ID: ENSG00000215475
  
Biological name :SIAH3
  
Synonyms : Q8IW03 / SIAH3 / siah E3 ubiquitin protein ligase family member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q14.13
Gene start: 45777243
Gene end: 45851736
  
Corresponding Affymetrix probe sets: 1560676_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000383256
NCBI entrez gene - 283514     See in Manteia.
OMIM - 615609
RefSeq - NM_198849
RefSeq Peptide - NP_942146
swissprot - Q8IW03
Ensembl - ENSG00000215475
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 siah2lENSDARG00000044381Danio rerio
 SIAH3ENSGALG00000026849Gallus gallus
 Siah3ENSMUSG00000091722Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIAH2 / O43255 / siah E3 ubiquitin protein ligase 2ENSG0000018178839
SIAH1 / Q8IUQ4 / siah E3 ubiquitin protein ligase 1ENSG0000019647038


Protein motifs (from Interpro)
Interpro ID Name
 IPR004162  E3 ubiquitin-protein ligase SIN-like
 IPR008974  TRAF-like
 IPR018121  Seven-in-absentia protein, TRAF-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:1903215 negative regulation of protein targeting to mitochondrion IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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