ENSG00000227345


Homo sapiens

Features
Gene ID: ENSG00000227345
  
Biological name :PARG
  
Synonyms : PARG / poly(ADP-ribose) glycohydrolase / Q86W56
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q11.23
Gene start: 49818279
Gene end: 49970203
  
Corresponding Affymetrix probe sets: 205060_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481064
Ensembl peptide - ENSP00000484285
Ensembl peptide - ENSP00000384408
Ensembl peptide - ENSP00000480645
NCBI entrez gene - 8505     See in Manteia.
OMIM - 603501
RefSeq - XM_011540305
RefSeq - NM_001303486
RefSeq - NM_001303487
RefSeq - NM_001303489
RefSeq - NM_001324381
RefSeq - NM_003631
RefSeq Peptide - NP_001311310
RefSeq Peptide - NP_003622
RefSeq Peptide - NP_001290416
RefSeq Peptide - NP_001290415
RefSeq Peptide - NP_001290418
swissprot - Q86W56
swissprot - A0A087WXI6
swissprot - A0A087WX07
Ensembl - ENSG00000227345
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pargaENSDARG00000061114Danio rerio
 PARGENSGALG00000002117Gallus gallus
 PargENSMUSG00000021911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007724  Poly(ADP-ribose) glycohydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:1990966 ATP generation from poly-ADP-D-ribose IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004649 poly(ADP-ribose) glycohydrolase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
POLB-Dependent Long Patch Base Excision Repair


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143799 PARP1 / P09874 / poly(ADP-ribose) polymerase 1  / reaction






 

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