ENSG00000241553


Homo sapiens

Features
Gene ID: ENSG00000241553
  
Biological name :ARPC4
  
Synonyms : actin related protein 2/3 complex subunit 4 / ARPC4 / P59998
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.3
Gene start: 9792495
Gene end: 9807726
  
Corresponding Affymetrix probe sets: 211672_s_at (Human Genome U133 Plus 2.0 Array)   217817_at (Human Genome U133 Plus 2.0 Array)   217818_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473435
Ensembl peptide - ENSP00000414751
Ensembl peptide - ENSP00000432235
Ensembl peptide - ENSP00000380431
Ensembl peptide - ENSP00000388169
Ensembl peptide - ENSP00000395085
NCBI entrez gene - 10093     See in Manteia.
OMIM - 604226
RefSeq - NM_001024959
RefSeq - NM_001024960
RefSeq - NM_001198780
RefSeq - NM_005718
RefSeq Peptide - NP_005709
RefSeq Peptide - NP_001020130
RefSeq Peptide - NP_001020131
RefSeq Peptide - NP_001185709
swissprot - P59998
swissprot - R4GN08
swissprot - F8WDW3
swissprot - F8WDD7
Ensembl - ENSG00000241553
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arpc4ENSDARG00000054063Danio rerio
 arpc4lENSDARG00000058225Danio rerio
 ARPC4ENSGALG00000006691Gallus gallus
 Arpc4ENSMUSG00000079426Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008384  Actin-related protein 2/3 complex subunit 4
 IPR034666  Arp2/3 complex subunit 2/4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030041 actin filament polymerization IEA
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IDA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0045010 actin nucleation NAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0061024 membrane organization TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex TAS
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0030674 protein binding, bridging IPI
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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